Publications by authors named "Sheryl L Hewko"
Article Synopsis
- - The study aimed to evaluate how effective the Curaçao criteria are over time for diagnosing hereditary hemorrhagic telangiectasia (HHT) in children, using data from a Toronto HHT clinic over a 19-year period.
- - Out of 116 patients studied, only 41% met the criteria for a definite diagnosis at their first visit, with younger children showing even lower rates; however, by the end of follow-up, 63% reached a definitive diagnosis.
- - While the number of patients meeting specific diagnostic criteria, like epistaxis and telangiectasia, increased over time, the overall accuracy for diagnosis remained low, suggesting that relying on clinical criteria alone may not adequately diagnose HHT in pediatric
Introduction: Acetaminophen is the only analgesic recommended for use during pregnancy. This use has recently been linked to childhood developmental disorders, a finding that requires further investigation. Adverse birth outcomes-preterm birth, low birthweight, and small for gestational age-are associated with increased risk of developmental disorders and can serve as intermediate outcomes when examining the impact of maternal acetaminophen use.
View Article and Find Full Text PDFMaternal Mental Health in Assisted and Natural Conception: A Prospective Cohort Study.
J Obstet Gynaecol Can
November 2019
Objective: This study sought to compare the pregnancy and postpartum self-reported mood and mental health status of women who conceived with assisted reproductive technology (ART) with those of women who conceived spontaneously.
Methods: In this prospective cohort study, 1176 pregnant women from prenatal clinics in the Ontario Birth Study were enrolled. In the pregnancy and the postpartum period, women who conceived with ART, including in vitro fertilization and intrauterine insemination, were compared with women who conceived spontaneously regarding depression and anxiety at 12-16 weeks and 24-28 weeks gestation and 6-10 weeks postpartum.
Background: Pregnancy and early childhood represent critical periods that impact health throughout the life-course. The Ontario Birth Study (OBS) is a pregnancy cohort study designed as a platform for research on pregnancy complications, maternal and infant health, and the developmental origins of health and disease.
Methods: Pregnant women <17 weeks gestational age were recruited between 2013 and 2015 from antenatal clinics at Mount Sinai Hospital, Toronto, Canada.