Traveling-waves of metal-containing monomer polymerization without diffusion and heat-transfer.

The new approach for modeling kinetics of complex spatial self-propagating traveling-wave reactions is proposed. This approach is intended to replace well-known reaction-diffusion equations and self-propagating high-temperature synthesis (SHS) as methods for mathematical modeling of spatial propagation of chemical reactions. A chemical kinetic model for frontal polymerization of metal-containing monomers under this approach is suggested.

[Multivariate analysis of genealogical markers in adults with primary immunodeficiencies].

Aim: To study the genealogy of adult patients with primary immunodeficiencies (PID) and to analyze its data in the relatives of these patients.

Materials And Methods: A genealogical analysis was carried out in 74 adult patients with PID and 200 adults without this condition, by examining groups of signs in the relatives in at least 4 generations, the genealogical markers were an atypical infectious and inflammatory process; allergic diseases; autoimmune diseases; the presence of relatives with cancers; cases of reproductive dysfunction; deaths from infectious diseases and/or cancers in children; and congenital malformations. The percentage of relatives with the above genealogical markers of the total number of the relatives in 4 generations was used as an indicator.

[ASSOCIATION OF POLYMORPHIC MARKERS IN GENES OF INNATE IMMUNITY IN PATIENTS WITH PERIODONTITIS AND INFLAMMATORY DISEASES OF UPPER RESPIRATORY TRACT].

Aim: Search of association of polymorphisms in DEFB1, IL-10, TNF-α and TLR2 genes with development of chronic generalized periodontitis in representatives of Ural region (Caucasian race).

Materials And Methods: 142 patients, that were split into 3 groups, took part in the study: a group of patients with periodontitis, a group with frequent inflammatory disease of upper respiratory tract and a comparison group--healthy donors. A study of polymorphic markers was carried out: DEFB1 (-44G/C), DEFB1 (-20A/G), IL-10 (-1082.

[Determinants of morbidity in the areas situated along the Techa and Iset Rivers].

Due to the massive pollution of the Techa-Iset river system with the radioactive sewage of the Mayak industrial association in the 1950s, the factors responsible for the incidence of diseases were studied in 5 districts of the Kurgan Region along the territory of which rivers flow. There is a direct relationship of children's morbidity to ambient air pollution. The determinants of adult morbidity are air pollution and water quality.

[Analysis of the health status of rural inhabitants in the Sverdlovsk Region, determination of leading factors].

There is an increase in primary and overall mortality in the Sverdlovsk regional areas exposed to eastern-Urals radiation traces. The children mostly commonly have diseases of the endocrine and nervous systems, sensory and respiratory organs. The adults have predominantly neoplasms, diseases of the nervous, digestive, and urogenital systems and sensory organs.

[Factors influencing morbidity rates in preschool children in the city of Orsk].

The comparative contribution of environmental factors to morbidity among the preschoolchildren of the town of Orsk was studied by applying currently available methods. Great morbidity is favoured by toxicosis during maternal second-half pregnancy, the poor health status of neonatal babies at birth and by the end of the first year of life, going to the nurseries where vegetable and calorie diets are not observed, the location of kindergartens in the areas with high traffic, high ambient air pollution with sulfuric anhydride and acid, and with substandard drinking water quality. Lower morbidity in children is in turn promoted by greater quantities of vegetables and fruits in the meals both at home and in the nurseries and kindergartens, over 2-month breast feeding, no adverse working conditions in their parents, as well as implementation of conditioning procedures in children.

[Comparative assessment of hemodynamic risk factors of glaucomatous optic neuropathy progress].

Comparative evaluation of the significance of hemodynamic factors of risk of progress of glaucomatous optic neuropathy has been carried out: blood flow velocity, blood flow resistance, blood pressure in the orbital artery-central retinal artery system, perfusion ocular pressure in connection with stabilization of glaucomatous process, and intraocular pressure were analyzed for a period of up to 16 years. The most significant factors were blood pressure in the orbital artery-central retinal artery system and perfusion ocular pressure, but not blood flow velocity. The leading factor indicating the risk of progress of optic neuropathy in primary glaucoma is ocular perfusion pressure.

[The evaluation of the effect of chemical and radiation factors on the health of the population in an industrial city].

Kamensk-Ural'skiy, Sverdlovsk Province, is one of the Russian industrial cities and towns exposed to a combination of radiation and chemical pollutions. This is a large industrial center of the mid-Urals, where enterprises of ferrous and nonferrous metallurgy, power engineering. Intensive chemical and radiation pollutions of Kamensk-Ural'skiy have an adverse impact on its population's health, which is manifested by higher morbidity rates among both children and adolescents.

[The hemodynamic characteristics of the central retinal artery and ophthalmic artery in atherosclerotic lesions of the carotid arteries based on the data from ultrasonic study methods].

Central retinal artery and orbital artery were examined by ultrasonograph in 348 patients with atherosclerosis of the carotid arteries. Doppler shift of frequency spectrum was detected in the central retinal artery, which is typical of the ischemic syndrome of the eye. Its characteristics include decreased diastolic component of velocity and increased resistance index.

[The surgical treatment of normotensive glaucoma].

The efficacy of surgical treatment of low (normal)-pressure glaucoma is validated on the basis of analysis of the disease progress risk factors. The risk factors are inadequate intraocular pressure (IOP) and insufficient blood supply to the optic nerve and retina. For stabilizing the glaucomatous process, IOP is to be reduced below 14 mm Hg.

[Measurement of allergen-specific IGG for diagnosis of atopic diseases in children].

The concentrations of allergen-specific IgE were measured in 146 children with respiratory, skin, and mixed forms of allergic diseases. The spectrum of the allergens was determined and specific features for each of the studied patient populations defined.

[The activity of the antioxidant system and membrane lipid peroxidation in hypertension patients].

With the view to study state of antioxidant protection and membrane lipid peroxidation (LPO) in hypertonic disease (HD) 200 patients with HD of I and II stage (WHO classification) were examined. Structural and functional state of myocardium was assessed echocardiographically. Enzymatic and non-enzymatic LPO, catalase and superoxide-dismutase activity were analyzed in erythrocytes.

[Structural and functional parameters of the myocardium and atrial natriuretic peptide in atrial fibrillation].

The plasma level of atrial natriuretic factor and its relation to intracardiac and systemic hemodynamic parameters were examined in patients with coronary heart, rheumatic and mitral valvular diseases, neurocirculatory dystonia which were complicated by atrial fibrillation. The concentration of atrial natriuretic factor was found to vary with the left ventricular myocardial mass, left atrial contractility, antiarrhythmic therapy intensity and efficacy.

[Glucocorticoid function of the adrenal cortex in patients with myocardial infarction: study of elimination of exogenous cortisol].

The paper yields the results of the study into the elimination of exogenous cortisol from the blood bed in 26 patients with myocardial infarction. It is concluded that the nature of cortisol elimination may reflect the natural history and prediction of myocardial infarction. In terms of the body tissue demand, two type of elimination are identified: retarded (a favorable type) and accelerated (an unfavorable type).

[Structural-functional state of the hypertensive heart and atrial natriuretic factor during treatment with nifedipine].

The time course of structural and functional parameters using echocardiography and the level of atrial natriuretic factor (ANF) employing immunoradiometric assay were examined in 37 patients with essential hypertension taking a 3-week therapy with nifedipine (corinfar) in doses individually chosen. The changes in the structural and functional parameters of the hypertensive heart were found to be associated with its endocrine function. A course therapy of patients with essential hypertension with nifedipine in individually based doses caused a significant rise in plasma ANF levels, a normalization of cardiac compensatory mechanism function.

[Prospects of the use of decompression surgery of the optic nerve in atrophy of vascular etiology].

The technique of decompression surgery on the optic nerve in vascular atrophy has been developed. Optic disk staining grew more intensive, visual field widened, and vision acuity improved after such surgery. Results of fluorescent angiography of the fundus oculi and ultrasonic dopplerography evidence an essential improvement of the blood stream in the central retinal artery after the operation.

[Correlation between the severity of atherosclerosis of cerebral, coronary and retinal vessels].

As a result of clinico-physiological examinations 643 patients suffering from cerebral atherosclerosis were divided into 3 groups by the severity of atherosclerosis of the cerebral vessels. These patients also exhibited atherosclerosis of the coronary and retinal vessels. Mathematical methods have been used to study the relationship and severity of atherosclerosis of the cerebral, coronary and retinal vessels.

[Hypophyseo-thyroid system in stress stenocardia and myocardial infarct with favorable and unfavorable course].

The condition of the hypophyseal-thyroid system in patients with angina of effort and in those with myocardial infarction in the acute stage was studied by determining the content in the blood of the thyrotropic hormone (TTH), thyroxin (T4), and triiodthyronine and 2-hour iodine uptake by the thyroid. It was found that the functional condition of the hypophyseal-thyroid system in patients with angina of effort differs essentially from that in patients with myocardial infarction. The behavior of the thyroid system in myocardial infarction is equivocal and correlates with the character of the course followed by the disease.