Publications by authors named "Sherry Yin"
Article Synopsis
- A study conducted in Los Angeles County assessed the effectiveness of the JYNNEOS vaccine against symptomatic mpox among men aged 18 and older who were eligible for vaccination between May 2022 and January 2023.
- Out of 2,171 confirmed mpox cases, 93% were unvaccinated, while the vaccine effectiveness was found to be 69% for partially vaccinated individuals and 84% for those fully vaccinated.
- Additionally, the vaccine offered different levels of protection based on HIV status, with fully vaccinated people living with HIV showing 72% effectiveness compared to 88% for those without HIV.
High prevalences of HIV and other sexually transmitted infections (STIs) have been reported in the current global monkeypox outbreak, which has affected primarily gay, bisexual, and other men who have sex with men (MSM) (1-5). In previous monkeypox outbreaks in Nigeria, concurrent HIV infection was associated with poor monkeypox clinical outcomes (6,7). Monkeypox, HIV, and STI surveillance data from eight U.
View Article and Find Full Text PDFIn-person instruction during the COVID-19 pandemic concerns educators, unions, parents, students, and public health officials as they plan to create a safe and supportive learning environment for children and adolescents (1). Los Angeles County (LAC), the nation's largest county, has an estimated population of 10 million, including 1.7 million children and adolescents aged 5-17 years (2).
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- Serologic assays for SARS-CoV-2 detect various antibody subtypes and utilize different target antigens.* -
- A comparison between the Spike-Protein ELISA and the Abbott ArchitectTM SARS-CoV-2 IgG assay showed they performed similarly.* -
- The tests had high concordance, meaning they generally agreed with each other, but there were a few rare instances of differing results.*
Article Synopsis
- The study explored how SARS-CoV-2 spreads within households in the U.S. and calculated the household secondary infection rate (SIR) to help develop strategies for reducing transmission.
- Researchers recruited patients with confirmed SARS-CoV-2 infections and their household members in Utah and Wisconsin, gathering demographic data and conducting tests over several visits.
- Results showed a 29% overall secondary infection rate, with higher rates among children and spouses, indicating that individuals with weakened immune systems or diabetes are at greater risk, suggesting the need for strict self-isolation measures.
Background And Objectives: Limited data exist on severe acute respiratory syndrome coronavirus 2 in children. We described infection rates and symptom profiles among pediatric household contacts of individuals with coronavirus disease 2019.
Methods: We enrolled individuals with coronavirus disease 2019 and their household contacts, assessed daily symptoms prospectively for 14 days, and obtained specimens for severe acute respiratory syndrome coronavirus 2 real-time reverse transcription polymerase chain reaction and serology testing.
Article Synopsis
- The study analyzed mild and asymptomatic cases of SARS-CoV-2 by observing 198 household contacts in Wisconsin and Utah during a 14-day period.
- Results showed that common symptoms upon positive COVID-19 testing included upper respiratory (68%) and neurological symptoms (64%), while fever was less commonly reported (19%).
- A notable 17% of participants were asymptomatic at the time of testing, but all eventually developed symptoms, highlighting the need for effective infection control and contact tracing measures.
In a household study, loss of taste and/or smell was the fourth most reported symptom (26/42 [62%]) among coronavirus disease 2019 (COVID-19) case patients and had the highest positive predictive value (83% [95% confidence interval [CI], 55%-95%) among household contacts. Olfactory and taste dysfunctions should be considered for COVID-19 case identification and testing prioritization.
View Article and Find Full Text PDFBackground: Civil registration and vital statistics (CRVS) systems play a key role in upholding human rights and generating data for health and good governance. They also can help monitor progress in achieving the United Nations Sustainable Development Goals. Although many countries have made substantial progress in strengthening their CRVS systems, most low- and middle-income countries still have underdeveloped systems.
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