Publications by authors named "Sherri Longobardi"
Article Synopsis
- The study aimed to find specific autoantibodies in patients with primary Sjögren's syndrome (SS) who test negative for anti-Ro/SS-A antibodies.
- Researchers analyzed plasma samples from SS patients and controls using advanced protein arrays, identifying novel autoantibody specificities in the process.
- The findings suggest that these autoantibodies could help identify a significant portion of Ro seronegative SS cases, potentially improving diagnosis and understanding of the disease.
The Edema Toxin (ET), composed of a Protective Antigen (PA) and the Edema Factor (EF), is a cellular adenylate cyclase that alters host responses by elevating cyclic adenosine monophosphate (cAMP) to supraphysiologic levels. However, the role of ET in systemic anthrax is unclear. Efferocytosis is a cAMP-sensitive, anti-inflammatory process of apoptotic cell engulfment, the inhibition of which may promote sepsis in systemic anthrax.
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