Publications by authors named "Shermyn Xiumin Neo"
Introduction: The decision to offer deep brain stimulation (DBS) to elderly patients with Parkinson's disease (PD) presents challenges due to higher perceived risks and uncertain long-term benefits. Here, we aimed to compare the outcomes after DBS for elderly versus non-elderly patients with PD.
Methods: We analyzed data from our institutional cohort and retrieved publicly available data through a systematic review.
Background: Sleep disorders are common in Parkinson's disease (PD). However, the longitudinal relationship between sleep quality and the other non-motor symptoms of PD has not been well characterized, especially in early PD.
Objective: To explore the value of baseline sleep quality in predicting the progression of other non-motor symptoms in early PD.
Syphilitic spinal disease is a rare condition caused by the spirochete Treponema pallidum, either from direct spirochete involvement of the cord or as a consequence of indirect spirochete involvement of the meninges, blood vessels, or the vertebral column. After the introduction of penicillin therapy in the 1940s, it has become an increasingly rare condition. We report 3 challenging cases of syphilitic spinal disease presenting as myelopathy-1 with an extra-axial gumma of tertiary syphilis causing cord compression and 2 with tabes dorsalis complicated by tabetic spinal neuroarthropathy-each presenting a diagnostic dilemma to their treating physicians.
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- Subjective cognitive complaints (SCC) and affective symptoms are common in early Parkinson's Disease (PD), with a prevalence of 38.8% found in a study of 121 participants.
- The study used well-defined criteria to assess cognitive impairment and various scales to measure anxiety, depression, and apathy, revealing significant associations primarily in cognitively normal participants.
- The findings suggest that SCC can indicate affective disorders in those without cognitive impairment, while in cognitively impaired individuals, it may underestimate the prevalence of Mild Cognitive Impairment (PD-MCI).
Parkinson's disease (PD) is a chronic neurodegenerative disease with complex motor and non-motor symptoms often leading to significant caregiver burden. An integrated, multidisciplinary care setup involving different healthcare professionals is the mainstay in the holistic management of PD. Many challenges in delivering multidisciplinary team (MDT) care exist, such as insufficient expertise among different healthcare professionals, poor interdisciplinary collaboration, and communication.
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