Publications by authors named "Sherleen Chen"
Purpose: To assess the rates of postoperative steroid response following dropless cataract surgery using a subconjunctival depot of triamcinolone versus conventional cataract surgery using topical prednisolone.
Patients And Methods: We reviewed consecutive cataract surgery cases performed by a single surgeon to determine the likelihood of steroid response, defined as intraocular pressure (IOP) 50% above baseline or IOP > 24 mmHg postoperatively, excluding the first 72 hours. Logistic regression models were performed including baseline characteristics as exposures in the model and steroid response as the outcome.
Article Synopsis
- The study found that patients with primary open-angle glaucoma (POAG) had a higher prevalence of autoimmune diseases (AiD), with 17.4% of POAG patients affected compared to 10.1% in control patients undergoing cataract surgery.
- Among POAG patients, rheumatoid arthritis and psoriasis were the most common AiDs identified.
- Having an AiD was associated with over two and a half times the odds of having POAG compared to controls, along with other risk factors like age and non-White ethnicity.
Purpose: To compare the intraocular lens calculation formulas and evaluate postoperative refractive results of patients with previous hyperopic corneal refractive surgery.
Design: Retrospective, comparative, observational study.
Setting: Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
Purpose Of Review: Continuous curvilinear manual capsulorhexis is currently the standard of cataract surgery. In the past several years, new technologies have been developed to improve the consistency and safety of capsulorhexis creation. This article reviews the most recent technologies in capsulotomy formation and their advantages and disadvantages.
View Article and Find Full Text PDFObjectives: To evaluate the impact of a comprehensive cataract surgery curriculum on the incidence of intraoperative complications.
Design: We retrospectively compared the total number of cataract surgeries that the residents performed in all of the teaching sites, and the incidences of intraoperative complications (anterior capsule tear, posterior capsule rent, vitreous loss, anterior vitrectomy, zonular dialysis, iris trauma, hemorrhage, dropped lens fragment, corneal wound burn, incorrect intraocular lens) for the surgeries performed at Massachusetts Eye & Ear by residents in the pre-intervention group (residents graduating in 2004 and 2005), before the implementation of a surgical curriculum, and the residents in the post-intervention group (residents graduating in 2014 and 2015).
Setting: Ophthalmology residency program at a major academic institution.
Objectives: To assess resident cataract surgery outcomes at an academic teaching institution using 2 Physician Quality Reporting System (PQRS) cataract measures, which are intended to serve as a proxy for quality of surgical care.
Design: A retrospective review comparing cataract surgery outcomes of resident and attending surgeries using 2 PQRS measures: (1) 20/40 or better best-corrected visual acuity following cataract surgery and (2) complications within 30 days following cataract surgery requiring additional surgical procedures.
Setting: An academic ophthalmology center.
Article Synopsis
- Residential history and solar exposure are potential risk factors for exfoliation syndrome (XFS), but detailed evaluation of solar exposure's impact on XFS was lacking prior to this study.
- This case-control study involved participants aged 60 and older from the U.S. and Israel, examining the relationship between latitude of residence and time spent outdoors with XFS risk.
- Findings revealed a significant correlation, with increased latitude and outdoor time linked to higher XFS odds, while wearing sunglasses during peak sun hours reduced the risk, particularly in the U.S.
Purpose: To investigate biomarker differences in routine preoperative blood tests performed on primary open-angle glaucoma (POAG) case and control patients presenting for anterior segment eye surgery.
Methods: POAG cases and age-related cataract surgery patients (controls) who underwent anterior segment surgery at Massachusetts Eye and Ear from January 2009 through March 2012 were identified by retrospective record review. Patients with diabetes mellitus, secondary glaucoma, and cataract due to trauma or steroid exposure were excluded.
Purpose: To evaluate the difference between target and actual refraction after phacoemulsification and intraocular lens implantation at an academic teaching institution's Comprehensive Ophthalmology Service.
Design: Retrospective study.
Participants: We examined 1275 eye surgeries for this study.
Purpose Of Review: Recent studies have focused on interventions to minimize progression of retinal disease in diabetic patients undergoing cataract surgery. Here, we review the evidence for progression of diabetic retinal disease with cataract surgery and critically analyze the interventions proposed to minimize it.
Recent Findings: Peri-operative intravitreal bevacizumab, sub-Tenon's triamcinolone, and panretinal photocoagulation (PRP) after cataract surgery (instead of before) have been examined as ways to improve cataract surgery results in diabetic patients.
Epithelial downgrowth is a rare, but potentially devastating, complication of intraocular surgery and trauma. It has been suggested that the incidence is declining with modern surgical techniques, but further long-term analysis is needed to determine whether this in fact is true. While clinical observations and experimental studies have helped to elucidate factors involved in the development of this disease, a precise understanding of its pathogenesis is unknown.
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