Publications by authors named "Sherin E Smallwood"
Article Synopsis
- Invitrogen's Gateway technology is a cloning method that simplifies the transfer of many open reading frames (ORFs) into plasmid vectors, making it effective for high-throughput purposes.
- MYXV, a poxvirus that infects only European rabbits and encodes 171 ORFs, uses this technology to create an ORF library, providing insights into its pathogenesis.
- MYXV shows potential for cancer treatment by targeting human cancer cell lines, making it a valuable model for researching poxvirus biology and developing oncolytic therapies.
Myxoma virus: propagation, purification, quantification, and storage.
Curr Protoc Microbiol
May 2010
Myxoma virus (MYXV) is a member of the Poxviridae family and prototype for the genus Leporipoxvirus. It is pathogenic only for European rabbits, in which it causes the lethal disease myxomatosis, and two North American species, in which it causes a less severe disease. MYXV replicates exclusively in the cytoplasm of the host cell.
View Article and Find Full Text PDF