Predictors of survival following liver transplantation in infants: a single-center analysis of more than 200 cases.

Background: Infants (<12 months) who require liver transplantation (LTx) represent a particularly challenging and understudied group of patients.

Methods: This retrospective study aimed to describe a large single-center experience of infants who received isolated LTx, illustrate important differences in infants versus older children, and identify pretransplant factors which influence survival. More than 25 pre-LTx demographic, laboratory, and operative variables were analyzed using the Log-rank test and Cox proportional hazards model.

Renal function impacts outcomes after intestinal transplantation.

Background: Although renal dysfunction (RD) has been commonly associated with poor outcome after other solid organ transplants, it has not been studied in detail after intestinal transplantation (ITx). Here we provide a detailed analysis of renal function after ITx, and identify predictors of post-ITx RD.

Methods: A retrospective analysis of patients undergoing ITx from 1991 to 2006 was performed.

Predictors of outcomes after pediatric liver transplantation: an analysis of more than 800 cases performed at a single institution.

Background: Pediatric liver transplantation (PLTx) is the standard of care for treatment of liver failure in children. Unfortunately, there are few studies with substantial numbers of patients that identify outcomes predictors. The goal of this study was to determine factors that influence outcomes in a large, single-center cohort of PLTx.

Effect of nonviral factors on hepatitis C recurrence after liver transplantation.

Objective: Hepatitis C (HCV) is now the most common indication for orthotopic liver transplantation (OLT). While graft reinfection remains universal, progression to graft cirrhosis is highly variable. This study examined donor, recipient, and operative variables to identify factors that affect recurrence of HCV post-OLT to facilitate graft-recipient matching.

Optimal utilization of donor grafts with extended criteria: a single-center experience in over 1000 liver transplants.

Objective: Severely limited organ resources mandate maximum utilization of donor allografts for orthotopic liver transplantation (OLT). This work aimed to identify factors that impact survival outcomes for extended criteria donors (ECD) and developed an ECD scoring system to facilitate graft-recipient matching and optimize utilization of ECDs.

Methods: Retrospective analysis of over 1000 primary adult OLTs at UCLA.

Analysis of long-term outcomes of 3200 liver transplantations over two decades: a single-center experience.

Objective: Few studies have evaluated long-term outcomes after orthotopic liver transplantation (OLT). This work analyzes the experience of nearly 2 decades by the same team in a single center. Outcomes of OLT and factors affecting survival were analyzed.

Fulminant liver failure due to usnic acid for weight loss.

The use of complementary and alternative medicine (CAM) in developed countries has increased significantly over the years. Among the most popular are the weight loss supplements or "fat burners." Liver failure due to these popular remedies has been widely recognized.