The effect of anticholinergic drugs on cognition of patients with Parkinson's disease: a cohort study from the Egyptian population.

Background: Cognitive dysfunction is a non-motor manifestation of Parkinson's disease (PD). We aimed to determine the frequency and patterns of cognitive dysfunction in treated patients with PD and their predictors.

Research Design And Methods: This study included 80 patients (male = 48; female = 32) and 30 healthy individuals.

The effect of epilepsy and antiseizure medications on cardiac autonomic functions in children with epilepsy.

Background: Autonomic manifestations have been frequently studied in adults with epilepsy. Here, we evaluated cardiac autonomic (ANS) functions in children with epilepsy in the interictal period and determined the risks for their dysfunctions.

Research Design And Methods: This study included 60 patients (boys = 25; girls = 35 age: 14.

The effectiveness of cerebrolysin, a multi-modal neurotrophic factor, for treatment of post-covid-19 persistent olfactory, gustatory and trigeminal chemosensory dysfunctions: a randomized clinical trial.

Background: This trial aimed to monitor the outcomes of persistent post-covid-19 smell and taste disorders after cerebrolysin therapy, a NTF, and olfactory and gustatory trainings.

Research Design And Methods: This was a prospective randomized trial. It included 250 patients (male = 93, female = 157; age: 31.

Evaluation of children and adults with post-COVID-19 persistent smell, taste and trigeminal chemosensory disorders: A hospital based study.

Background: Smell disorders are the most frequent persistent coronavirus disease 2019 (COVID-19) complications.

Aim: To describe the patterns and characteristics of persistent smell and taste disorders in Egyptian patients.

Methods: Assessment was done to 185 patients (adults = 150, age: 31.

Evaluation of chronic idiopathic tinnitus and its psychosocial triggers.

Background: The tinnitus susceptibility patterns in relation to different psychological and life stressors are unknown in different cultures.

Aim: To determine the comorbid psychosocial factors and behaviors associated with tinnitus and the predictors for the increase in its severity.

Methods: Participants were 230 adults (males = 70; females = 160; mean age = 38.

Idiopathic steno-occlusive disease with bilateral internal carotid artery occlusion: A Case Report.

Background: Moyamoya disease (MMD) is a rare cause of acute stroke and transient ischemic attacks in children. We described clinical, diagnostic features and follow-ups of a young child with acute stroke.

Case Summary: We report a 4-year-old girl with left hemiparesis after an acute ischemic stroke.

Vestibular function in children with generalized epilepsy and treated with valproate.

Background: Studies that evaluated vestibular function with epilepsy are fewer than auditory studies. We assessed vestibular function in children with epilepsy in inter-ictal period.

Research Design And Methods: This cross-sectional study included 35 children with generalized epilepsy (boys=15; girls=20; age=11.

Peripartum depression and its predictors: A longitudinal observational hospital-based study.

Background: Depression is a common problem in women in childbearing years due to burdens of motherhood and building a family. Few studies estimate the prevalence of antepartum depression compared to those in the postpartum period.

Aim: To estimate the prevalence and the severities of peripartum depression and major depressive disorder and their predictors.

Vestibular function for children with insulin dependent diabetes using cervical vestibular evoked myogenic potentials testing.

Background: Healthy vestibular system adjusts balance during static and dynamic conditions. This is important for normal development (standing up and walking). Vestipulopathies (central and peripheral) are common complications of diabetes in adult population.

Behavioral assessment of children and adolescents with Graves' disease: A prospective study.

Previous studies have identified frequent comorbid neuropsychiatric disorders and conditions in adults with thyrotoxicosis. These studies are scarce or even lacking in pediatric population. This work aimed to study the behavior of children and adolescents with Graves' disease (GD).

Restless leg syndrome in patients with chronic kidney disease: a hospital-based study from Upper Egypt.

Objectives: Chronic kidney disease (CKD) is a common cause of restless leg syndrome (RLS). RLS is under-recognized, misdiagnosed and undertreated disorder in our locality. In this study, we aimed to determine the prevalence of RLS due to CKD and its predictors.

Behavioral problems in children with primary monosymptomatic nocturnal enuresis.

Background And Objectives: Primary monosymptomatic nocturnal enuresis (PMNE) is a common distressing condition to children and parents. This study aimed to determine frequencies, severities and characteristics of behavioral problems with PMNE.

Methods: This cross-sectional study included 80 children with PMNE (age: 12.

The Effect of Epilepsy and Antiepileptic Drugs on Cortical Motor Excitability in Patients With Temporal Lobe Epilepsy.

Objectives: Transcranial magnetic stimulation (TMS) has been used to assess cortical disinhibition/excitation with epilepsy and determine the degree of patients' response to antiepileptic drugs (AEDs). However, the results of studies are variable and conflicting. We assessed cortical motor excitability in adults with temporal lobe epilepsy (TLE).

Behavioral assessment of females with congenital adrenal hyperplasia.

Purpose: Patients with congenital adrenal hyperplasia (CAH) have an increased risk of psychological/psychiatric symptoms and disorders. This study aimed to assess the behavior of girls with CAH and its independent risk variables.

Methods: This cross-sectional study included 55 girls with CAH due to 21-hydroxylase deficiency (mean age 12.

Cortical excitability in epilepsy and the impact of antiepileptic drugs: transcranial magnetic stimulation applications.

Introduction: Epileptic conditions are characterized by impaired cortical excitation/inhibition balance and interneuronal disinhibition. Transcranial magnetic stimulation (TMS) is a neurophysiological method that assesses brain excitation/inhibition.

Area Covered: This review was written after a detailed search in PubMed, EMBASE, ISI web of science, SciELO, Scopus, and Cochrane Controlled Trials databases from 1990 to 2020.

Sexual functions in women with focal epilepsy: Relationship to demographic, clinical, hormonal and psychological variables.

Objectives: Sexual dysfunctions [SDs] are common in women with epilepsy [WWE] but related studies were neglected in our locality. We aimed to determine the frequencies and severities of SDs and their clinical, hormonal and psychological determinants in WWE.

Patients And Methods: This study included 120 adults [mean age: 36.

Psychogenic nonepileptic seizures in adults with epilepsy: a tertiary hospital-based study.

Many studies describe and characterize psychogenic nonepileptic seizures (PNES) in high-income but few come from low/middle and low income countries. We aimed to determine the prevalence of PNES coexisted in adults with epilepsy and to characterize their semiology, comorbidities and predictors whether presented with epilepsy ( = 563) or alone ( = 73). Patients were recruited from a tertiary referral epilepsy clinic.

Psychosis in adults with epilepsy and its relationship to demographic, clinical and treatment variables.

: Psychiatric symptoms and disorders are commonly reported with epilepsy. This study aimed to determine the prevalence of interictal psychosis (IIP) in adults with epilepsy and its risk predictors. : The study included 710 patients (mean age: 36.

Cognitive function in children with classic congenital adrenal hyperplasia.

Studies of cognitive function in patients with congenital adrenal hyperplasia (CAH) are few and controversial. This study aimed to investigate general intelligence and specific cognitive functions in children with salt wasting (SW) form of CAH and their relationship to demographic, clinical, and laboratory variables. This study included 36 children with classic 21 hydroxylase deficiency SW type of CAH (males = 12; females = 24; mean age = 15.

Sexual Dysfunctions Induced by Pregabalin.

Objectives: Pregabalin (PGB) is a gabapentinoid (ie, GABA analog), which has been Food and Drug Administration-approved for treatment of partial epilepsy in adults and neuropathic pain. It also has off-label uses for the treatment of generalized anxiety disorders, fibromyalgia, and tension headache and prevention of migraine. Few cases were reported with sexual dysfunctions (SDs) as adverse effects of PGB and gabapentin, and the majority were dose related (≥900 mg/d for gabapentin).

Cardiac autonomic function in children with type 1 diabetes.

Unlabelled: Cardiovascular autonomic neuropathy (CAN) is a major complication of type 1 diabetes (T1D). This study aimed to evaluate cardiac autonomic nervous system (ANS) function in children with T1D and its relation to different demographic, clinical and laboratory variable. This cross-sectional study included 60 children with T1D (mean age = 15.

Topiramate induced peripheral neuropathy: A case report and review of literature.

Drug-induced peripheral neuropathy had been rarely reported as an adverse effect of some antiepileptic drugs (AEDs) at high cumulative doses or even within the therapeutic drug doses or levels. We describe clinical and diagnostic features of a patient with peripheral neuropathy as an adverse effect of chronic topiramate (TPM) therapy. A 37-year-old woman was presented for the control of active epilepsy (2010).

The effect of antiepileptic drugs on the kidney function and structure.

Long-term use of antiepileptic drugs (AEDs) is associated with number of somatic conditions. Data from experimental, cross-sectional and prospective studies have evidence for the deleterious effect of some AEDs on the kidney. Areas covered: This review summarized the current knowledge of the effect of AEDs on the kidney including evidence and mechanisms.

Migraine in Assiut Governorate, Egypt: epidemiology, risk factors, comorbid conditions and predictors of change from episodic to chronic migraine.

Objectives: Headache is one of the most common complaints in medicine. Epidemiological and population-based studies reported that migraine has a variable prevalence worldwide. This study was done to estimate the prevalence of migraine across various age groups in Assiut district, Egypt.