The Impact of Depressive Symptoms on Neuropsychological Performance Tests in HIV-Infected Individuals: A Study of the Hawaii Aging with HIV Cohort.

BACKGROUND: The frequency of neurocognitive impairment (NCI) in human immunodeficiency virus (HIV)-infected individuals remains high despite the availability of potent antiretroviral therapy (ART). The concurrence of depression among HIV-infected patients with NCI is common, especially among older individuals. Depression has been implicated as a risk factor for impaired neuropsychological performance (NP).

Ethnic differences in hiv disease progression: a comparison of Asian/Pacific Islanders and Whites living in Hawaii.

Objective: To characterize the association of demographic factors with the relative hazards (RH) of developing AIDS or death among HIV-infected individuals of Asian/Pacific Islander (API) ethnicity and Whites.

Design: Cohort study

Setting: Hawaii State Health Department database of HIV-infected individuals

Patients Or Participants: Hawaii Sero-Positivity and Medical Management (HSPAMM) program participants from January 1989 to November 2002

Interventions: None

Main Outcome Measures: Differences in the time to develop AIDS or death among HIV-infected individuals who reported being on highly active antiretroviral treatment (HAART) were examined by ethnicity, income, and CD4+ cell counts at HAART initiation by using Kaplan-Meier survival analysis and Cox proportional hazard analyses.

Results: The study was based on 516 HIV-infected individuals, who were primarily White (61.

A descriptive epidemiologic study of HIV-infected individuals in Hawaii: report of the Hawaii Sero-Positivity and Medical Management database (HSPAMM).

This is a retrospective study of the HSPAMM database evaluating differences in clinical, laboratory, HIV-risk factors and demographic characteristics with respect to gender and ethnicity. There were no significant differences comparing gender, and Hawaiians and non-Hawaiians with respect to developing a CD4 count < 200 cells/mm3. HSPAMM contains information on a large number of HIV-infected Asians/Pacific Islanders.

Molecular analysis and pathology of a second pediatric HIV-associated Burkitt lymphoma.

Diagnosis of a second HIV-associated non-Hodgkin lymphoma (HIV-NHL) is rare, but additional cases may occur as aggressive therapy for both HIV and NHL improves. An 11-year-old presented with a second primary HIV-NHL following remission for 9 years. Analysis of the tumor demonstrated presence of EBV and HIV with absence of CMV, HHV-8, and HHV-6.