Publications by authors named "Sheri Ramaker"

Article Synopsis
  • A study was conducted to determine if injecting botulinum toxin A (BTX-A) into the pectoralis major muscle during breast reconstruction could reduce pain and improve physical well-being in women undergoing tissue expansion.
  • The study involved 131 women, with some receiving the BTX-A injection while others received a placebo, and utilized pain intensity and the BREAST-Q scale to measure outcomes.
  • Results showed no significant difference in pain levels or physical well-being between the BTX-A group and the placebo group, indicating that the injection did not provide the expected benefits.
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Globally breast cancer is the leading cause of cancer death among women. The breast consists of epithelium, stroma and a mucosal immune system that make up a complex microenvironment. Growing awareness of the role of microbes in the microenvironment recently has led to a series of findings important for human health.

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Background: In this 2-site randomized trial, we investigated the effect of antiseptic drain care on bacterial colonization of surgical drains and infection after immediate prosthetic breast reconstruction.

Methods: With IRB approval, we randomized patients undergoing bilateral mastectomy and reconstruction to drain antisepsis (treatment) for one side, with standard drain care (control) for the other. Antisepsis care included both: chlorhexidine disc dressing at drain exit site(s) and irrigation of drain bulbs twice daily with dilute sodium hypochlorite solution.

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