The effectiveness of physical therapy in the rehabilitation of patients after arthroscopy of the knee joint.

Objective: Aim: To determine the effectiveness of physical therapy on the functional state of law enforcement officers' knee joints after surgical intervention.

Patients And Methods: Materials and Methods: The research involved law enforcement officers from different units of the National Police of Ukraine (n = 56) who had suffered knee joint injuries in the line of duty, and underwent surgical intervention and rehabilitation procedures.

Results: Results: It was found that 78.

[Effect of inhibitors serine/threonine protein kinases and protein phosphatases on mitosis progression of synchronized tobacco by-2 cells].

In order to investigate the role of various serine/ threonine protein kinases and protein phosphatases in the regulation of mitosis progression in plant cells the influence of cyclin-dependent (olomoucine) and Ca2+ -calmodulin-dependent (W7) protein kinases inhibitors, as well as protein kinase C inhibitors (H7 and staurosporine) and protein phosphatases inhibitor (okadaic acid) on mitosis progression in synchronized tobacco BY-2 cells has been studied. It was found that BY-2 culture treatment with inhibitors of cyclin dependent protein kinases and protein kinase C causes prophase delay, reduces the mitotic index and displaces of mitotic peak as compare with control cells. Inhibition of Ca2+ -calmodulin dependent protein kinases enhances the cell entry into prophase and delays their exit from mitosis.

[Peculiarities of urinary bladder cancer tumor cells apoptosis response on neoadjuvant chemotherapy].

Induced apoptosis in urinary bladder cancer tumor cells of patients was studied using TUNEL reaction. It was shown that increase in induced apoptosis value had a definite correlation between corresponding features of tumor reaction as a response on Gemcitabine-Cisplatin neoadjuvant chemotherapy application. It was found that evaluation of induced apoptosis in urinary bladder cancer tumor cells using TUNEL method allows forecasting the effectiveness of chemotherapy on the cellular level in patients with this type of cancer.

[The effect of inhibitors of serinethreonine protein kinases on Arabidopsis thaliana root morphology and microtubules organization in its cells].

The effect of different types of serine/thereonine protein kinases inhibitors (cyclin-dependent, Ca2+-calmodulin-dependent and protein kinase C) on microtubules organization in cells of Arabidopsis thaliana main primary root zones were investigated in vivo. The microtubules in epidermal and cortex cells in the transition and elongation zones as well as microtubules in trichoblasts and atrichoblasts in the differentiation zone showed the greatest sensitivity to protein kinases inhibitors studied. It was established that microtubules in these cell types modified their initial transverse/oblique orientation to a chaotic or longitudinal relative to the major axis of primary root as a result of serinethereonine protein kinases inhibition.

[Reorganization of microtubules as a response to realization of NO (II) signal pathways in plant cell].

Effects of exogenic NO donor, sodium nitroprusside, on orientation and organization of cortical microtubules in Arabidopsis thaliana root cells that express GFP-MAP4 were studied in vivo. It was found that sodium nitroprusside treatment (10-500 microM, 24 h) caused the acceleration of primary root growth and enhanced initiation of root hairs in differentiation zone. The influence of sodium nitroprusside revealed in alterations of cortical: microtubules orientation and organization in different types of cells of A.

[The effect of okadaic acid on root morphology of Arabidopsis thaliana and microtubule organization in its cells].

To investigate the functional role of protein hyperphosphorylation in plant cells the general morphology of Arabidopsis thaliana primary roots and structural-functional property of cortical microtubules were studied after treatment with okadaic acid, specific inhibitor of protein phosphatases PPI and PP2A. It has been estimated that okadaic acid affects microtubule organization in a different manner depending from the type of the cells and functional zones of the primary root. It was found that the microtubules in epidermis and cortex cells of distal elongation zone which depolymerized after inhibitor treatment were the most sensitive to 0, 1, 1 and 10 nM okadaic acid concentrations.

[The role of typological differences in animal behavior during the process of adaptation to extreme situations].

In relation to Cosmos experiments behavioural responses of rhesus monkeys were investigated and compared with their conditioned reflex activities. The animals with a distinct search-oriented behaviour showed a higher rate of recovery of instrumented reflexes, better stability of conditioned-reflex activities to stress-effects and a faster adaptation to them. Extreme effects associated with changes in the experimental environment and rigid fixation inhibited conditioned-reflex activities to a greater extent than strong but short-term exposures followed by tests in a normal environment.

[Typological characteristics of conditioned reflex learning in monkeys].

Three types of conditioned learning dynamics were singled out in males of the rhesus monkeys by the speed of formation of a positive motor instrumental reflex and differentiation. Type I is characterized by the fastest mastering of separate subprograms and of the whole test program of conditioned behaviour, by optimal functional characteristics in the process of learning and by a high adaptivity in new conditions. The most prolonged formation of the conditioned reflexes occurs in monkeys of the III-d type; 50% of them do not master the whole learning program; monkeys with such type of learning dynamics have no adaptation of previously acquired conditioned stereotype to new environmental conditions.