Publications by authors named "Shereen Kholosy"
Article Synopsis
- Highly pathogenic avian influenza (HPAI) H5N1 viruses are prevalent in Egyptian poultry and are linked to human infections, necessitating a study of their genetic evolution from 2006 to 2014.
- The research utilized methods like Bayesian Markov Chain Monte Carlo for estimating evolutionary rates and SLAC for analyzing selection pressures, examining 368 full-length hemagglutinin (HA) sequences from various poultry types and regions.
- Findings showed two main virus subgroups evolved from a single introduction, with subgroup 2.2.1.2 exhibiting a higher evolution rate and both subgroups under positive selection, featuring notable mutations that may influence virus behavior.
