A Qualitative Exploration of the Process and Experience of Change in Moving on in My Recovery: An Acceptance and Commitment Therapy Based Recovery Group for Substance Use Disorder.

Moving on in my recovery (MOIMR) is a new, acceptance and commitment therapy (ACT) based group intervention to support recovery from substance use disorder. It was co-developed by, and is co-facilitated with, people in recovery. This study used a grounded theory model to understand the process of change experienced by individuals who completed the group programme.

Investigating the impact of 1 hour of daily outdoor access on the gait and hoof health of nonclinically lame cows housed in a movement-restricted environment.

Tiestalls, known for restrictive housing, can reduce cows' locomotor skills over time. While outdoor access benefits clinically lame cows, its effect on nonclinically lame cows is less known. This study evaluated 1 h daily outdoor access on gait and hoof health of nonclinically lame Holstein cows in tiestalls.

Descriptive evaluation of a camera-based dairy cattle lameness detection technology.

Lameness in dairy cattle is a clinical sign of impaired locomotion, mainly caused by painful foot lesions, compromising the US dairy industry's economic, environmental, and social sustainability goals. Combining technology and on-farm data may be a more precise and less labor-intensive lameness detection tool, particularly for early detection. The objective of this observational study was to describe the association between average weekly autonomous camera-based (AUTO) locomotion scores and hoof trimming (HT) data.

A service evaluation of measuring fluid responsiveness in acutely unwell hypotensive patients outside of critical care.

Introduction: Early recognition and prompt, appropriate management may reduce mortality in patients with sepsis. The Surviving Sepsis Campaign's guidelines suggest the use of dynamic measurements to guide fluid resuscitation in sepsis; although these methods are rarely employed to monitor cardiac output in response to fluid administration outside intensive care units. This service evaluation investigated the introduction of a nurse led protocolised goal-directed fluid management using a non-invasive cardiac output monitor to the standard assessment of hypotensive ward patients.

Prepartum behaviors as early indicators for postpartum energy associated biomarkers status in Holstein dairy cows.

Our main aim was to investigate the predictive value of prepartum behaviors such as total daily rumination (TDR), total daily activity (TDA) and dry matter intake (DMI) as early indicators to detect cows at risk for hyperketonemia (HYK), hypoglycemia (HYG) or high non-esterified fatty acid (NEFA) status in the first (wk1) and second week (wk2) postpartum. In a case control study, 64 Holstein cows were enrolled 3 weeks before the expected time of calving and monitored until 15 days in milk (DIM). Postpartum blood samples were taken at D3 and D6 for wk1 and at D12 and D15 for wk2 to measure beta-hydroxybutyrate, NEFA and glucose concentration.

Randomized clinical trial evaluating the effects of administering acidogenic boluses at dry-off on udder health, milk yield, and herd removal.

Acidogenic boluses can mitigate potential negative effects of high milk yield at dry-off on udder health. This randomized controlled trial aimed to investigate the effect of administering acidogenic boluses at dry-off on dry period intramammary infection (IMI) dynamics and on milk production parameters, somatic cell count linear score (LSCC), clinical mastitis (CM), and herd removal in the next lactation. A total of 901 cows from 3 dairy farms were randomly allocated to a control (CON, n = 458; no administration of acidogenic boluses at dry-off) or treatment group (TRT, n = 443; administration of 2 acidogenic boluses at dry-off).

A randomized clinical trial evaluating the effects of administration of acidogenic boluses at dry-off on rumination and activity behavior in the 14 subsequent days.

Elevated milk production at dry-off can lead to increased udder pressure and, in turn, increased stress due to pain and discomfort, affecting natural behaviors. Administering acidogenic boluses at dry-off acts by inducing temporary and mild decreases in blood pH. This decreases dry matter intake, reduces milk yield, and increases cow comfort by lessening udder pressure.

The Association between Prepartum Rumination Time, Activity and Dry Matter Intake and Subclinical Hypocalcemia and Hypomagnesemia in the First 3 Days Postpartum in Holstein Dairy Cows.

Changes in prepartum behaviors such as total daily rumination (TDR), total daily activity (TDA) and dry matter intake (DMI) have the potential to be used as early indicators for cows at risk for subclinical hypocalcemia (SCH) or hypomagnesemia (HYM) after calving. Our objective was to investigate associations between average daily rate of change in total daily rumination (ΔTDR), total daily activity (ΔTDA) and dry matter intake (ΔDMI) from -3 days prepartum to calving with SCH and HYM at D0 or D3 relative to calving. Prepartum TDR, TDA and DMI were measured in 64 Holstein dairy cows.

An iterative approach to the development of a sole ulcer induction model in Holstein cows.

Our objective was to develop a sole ulcer (SU) induction model that can be used to investigate new and more efficacious methods for the treatment and prevention of SU. Three iterations [phase (P)1, P2, and P3] of an SU induction model designed to mimic mechanical and presumed metabolic pathways for SU development were conducted. The results from P1 and P2 identified alterations for the subsequent phase.

Applications of Technology to Record Locomotion Measurements in Dairy Cows: A Systematic Review.

Lameness within the dairy industry is a concern because of its associated costs and welfare implications. Visual locomotion scoring has been commonly used for assessing cows' locomotion quality, but it can have low reliability and is relatively subjective compared to automated methods of assessing locomotion. Kinematic, kinetic, and accelerometric technologies can provide a greater number of more detailed outcome measurements than visual scoring.

Technology applications in bovine gait analysis: A scoping review.

Quantitative bovine gait analysis using technology has evolved significantly over the last two decades. However, subjective methods of gait assessment using visual locomotion scoring remain the primary on-farm and experimental approach. The objective of this review is to map research trends in quantitative bovine gait analysis and to explore the technologies that have been utilized to measure biomechanical parameters of gait.

Exploring the role of milk yield in the first week of lactation on the association between hyperketonemia and reproductive performance in dairy cattle.

The objective of this retrospective cohort study was to investigate whether the association of hyperketonemia (HYK) with reproductive performance differs based on milk production during the first week of lactation (wk 1). Data between calving and 150 d in milk (DIM) from 2,091 Holstein dairy cows from 5 commercial dairy herds in Minnesota were collected. The concentration of β-hydroxybutyrate (BHB) was measured twice between 3 and 10 DIM in whole blood to diagnose HYK (defined as BHB ≥1.

Assessment of milk yield and composition, early reproductive performance, and herd removal in multiparous dairy cattle based on the week of diagnosis of hyperketonemia in early lactation.

The purpose of this retrospective cohort study was to evaluate the effects of the timing of hyperketonemia (HYK) diagnosis during early lactation on milk yield and composition, reproductive performance, and herd removal. Plasma β-hydroxybutyrate (BHB) was measured twice a week during the first 2 wk of lactation in 362 multiparous Holstein cows for the diagnosis of HYK. In each week, cows were diagnosed as HYK positive (HYK+) if the plasma BHB concentrations were ≥1.

The effect of housing tiestall dairy cows in deep-bedded pens during an 8-week dry period on gait and step activity.

Increasing locomotor activity can improve leg health and decrease the prevalence of lameness in dairy cows. The dry period offers an opportunity to provide alternative housing to tiestall (TSL) cows that can increase locomotor activity. The objective was to determine whether housing TSL dairy cows in a deep-bedded loose pen (LP) during the 8-wk dry period affected gait and step activity.

Association of Body Condition Score and Score Change during the Late Dry Period on Temporal Patterns of Beta-Hydroxybutyrate Concentration and Milk Yield and Composition in Early Lactation of Dairy Cows.

Monitoring the body condition score (BCS) of dairy cows is a management strategy that can assist dairy producers in decision-making. The BCS and its variations reflect the level of body fat reserves and fat mobilization throughout the different stages of lactation. Cows that mobilize excessive amounts of fat reserves in response to the increased energy requirements of the transition period are more likely to have higher beta-hydroxybutyrate (BHB) concentration in blood, leading to a higher incidence of hyperketonemia postpartum.

The hidden cost of disease: I. Impact of the first incidence of mastitis on production and economic indicators of primiparous dairy cows.

Mastitis is a highly prevalent disease, which negatively affects cow performance, profitability, welfare, and longevity. The objectives of this study were (1) to quantify the impact of the first instance of mastitis, at different stages of lactation, on production and economic performance, and (2) to further quantify the impact of the first instance of mastitis when only cows that remain in the herd for at least 100 d in milk (DIM) and those that remain for 305 DIM are included in the analysis. A retrospective longitudinal study was conducted using data from existing animal health record files and Dairy Herd Improvement records.

The hidden cost of disease: II. Impact of the first incidence of lameness on production and economic indicators of primiparous dairy cows.

Lameness is a persistent and underreported health and welfare problem in the dairy industry, resulting in reduced cow performance and profitability as well as early culling. The study objectives were (1) to quantify the impact of the first instance of lameness, at different stages of lactation, on production and economic performance, and (2) to further quantify the impacts of the first instance of lameness when only cows that remain in the herd for at least 100 d in milk (DIM) and those that remain for 305 DIM are included in the analysis. A retrospective longitudinal study was conducted using pre-existing data from animal health records and Dairy Herd Improvement Association records.

Graduate Student Literature Review: The effect of housing systems on movement opportunity of dairy cows and the implications on cow health and comfort.

Intensification within the dairy industry has led to an increase in use of more restrictive indoor housing systems (most commonly tiestalls and freestalls) and less use of the pasture-based housing systems used in past generations. These indoor housing systems are associated with not only a higher level of restriction to cow movement, but also with a higher prevalence of lameness and cow comfort issues on farm, which negatively affects cow welfare, public perceptions, and producer profitability. In looking for solutions to these issues, several studies have investigated different housing and management options that are less restrictive and increase cow movement opportunity.

Housing tiestall dairy cows in deep-bedded pens during an 8-week dry period: Effects on lying time, lying postures, and rising and lying-down behaviors.

Dairy cow lying behavior is useful in determining the cow's level of welfare, as well as in determining how her environment may affect her comfort and ease of movement. In tiestall systems, cows usually remain in a stall for the duration of their lactation. The dry period offers a unique opportunity to provide alternative housing to the cow with minimal effects on farm housing and management.

Preventing Severe Asthma Exacerbations in Children. A Randomized Trial of Mite-Impermeable Bedcovers.

Rationale: Allergen exposure in sensitized individuals with asthma interacts with viruses to increase the risk of asthma exacerbation.

Objectives: To evaluate the use of house dust mite-impermeable bedding and its impact on severe asthma exacerbations in children.

Methods: We randomized mite-sensitized children with asthma (ages 3-17 yr) after an emergency hospital attendance with an asthma exacerbation to receive mite-impermeable (active group) or control (placebo group) bed encasings.

Adjuvant immunotherapy of high risk stage I melanoma with transfer factor.

Following conventional surgical management, 100 patients with high risk Stage I melanoma were treated with transfer factor to reduce the incidence of disease recurrence. All patients had primary lesions invasive to Clark's level III or deeper and exceeding 1.0 mm in measured thickness.