Publications by authors named "Shengzhou Zheng"

Article Synopsis
  • Hepatocellular carcinoma (HCC) is a serious cancer with late diagnosis and poor outcomes; this study focused on creating a gene signature to improve prognosis prediction.
  • Using machine learning on multiple patient cohorts, researchers identified 119 key genes, narrowing it down to a four-gene signature that effectively predicts survival and treatment response.
  • The study establishes the HCC prognosis-related gene signature (HPRGS) as a valuable tool for guiding treatment decisions and improving survival rates in HCC patients.
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Objectives: To compare the sensitivities of individual and combined sonography of hyperechoic aggregates and the double-contour sign in detecting monosodium urate (MSU) crystal deposits in gouty joints.

Methods: Monosodium urate crystal deposits in symptomatic and contralateral asymptomatic joints of 70 patients with acute gout were evaluated by sonography of hyperechoic aggregates and the double-contour sign individually and in combination. All patients with acute gout in this study had at least 1 symptomatic joint with MSU deposits determined by dual-energy computed tomography.

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Background: Tissue Doppler imaging (TDI) has provided an objective means to quantify global and regional left ventricular (LV) and right ventricular (RV) function with improved accuracy and greater reproducibility than conventional echocardiography. This study was conducted to assess RV myocardial systolic activation by TDI in subjects with pulmonary arterial hypertension (PAH).

Methods: A total of 30 patients with PAH and 30 healthy volunteers, all comparable in age and sex, underwent standard Doppler echo and TDI.

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Objective: To investigate the relationship between right ventricular (RV) mechanical delay and RV dysfunction in patients with pulmonary hypertension (PH).

Methods: A total of 51 patients with PH were divided into mild, moderate and high PH groups and 30 healthy volunteers served as control group. RV mechanical delay (defined as the difference in time to peak systolic annular velocity between the RV free wall and the ventricular septum) and RV fractional area change were obtained on apical four chamber view with Quantitive Tissue Velocity Imaging (QTVI).

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