Construction of pyridine-functionalized metal-organic frameworks for the detection of flazasulfuron.

Two novel Cu-based metal-organic frameworks (MOFs), namely, poly[[aquadichlorido[μ-4'-(pyridin-4-yl)-[2,2':6',2''-terpyridine]-4,4''-dicarboxylato][μ-4'-(pyridin-4-yl)-[2,2':6',2''-terpyridine]-4,4''-dicarboxylato]tricopper(II)] monohydrate], {[Cu(CHNO)Cl(HO)]·HO} or {[Cu(PTP)Cl(HO)]·HO}, (I), and poly[[diaquabis[μ-4'-(pyridin-3-yl)-[2,2':6',2''-terpyridine]-4,4''-dicarboxylato]bis(μ-terephthalato)tricopper(II)] dihydrate], {[Cu(CHNO)(CHO)(HO)]·2HO} or {[Cu(BDC)(MTP)(HO)]·2HO}, (II), have been synthesized successfully with 4'-(pyridin-4-yl)-[2,2':6',2''-terpyridine]-4,4''-dicarboxylic acid (HPTP) and 4'-(pyridin-3-yl)-[2,2':6',2''-terpyridine]-4,4''-dicarboxylic acid (HMTP) as the ligands, respectively. Crystal structure analysis reveals that (II) possesses a 2D coordinated layer structure, in which adjacent 2D coordination layers are linked into 3D frameworks through π-π interactions, while the structure of (I) displays dual coordination layers, in which adjacent coordination layers are connected into a 3D framework through hydrogen-bonding interactions. The photophysical properties of the two MOFs were investigated by fluorescence spectroscopy.

Fabrication of a 2D metal-organic framework (MOF) nanosheet colloidal system and investigation of its fluorescence response to pesticide molecules.

Pesticides, as a type of toxic chemicals widely used for a long time, not only pollute the environment but also affect people's health and cause serious harm to the human body, soil and environment. Therefore, it is very necessary to exploit a portable and environmentally friendly method to detect pesticides with high sensitivity. Herein, a new luminescent metal-organic framework ([Zn(TPYBDC)·HO], TPYBDC = 4'-(pyridin-4-yl)-[2,2':6',2''-terpyridine]-4,4''-dicarboxylate) with 2D coordination layers has been designed and assembled using 4'-(pyridin-4-yl)-[2,2':6',2''-terpyridine]-4,4''-dicarboxylic acid as the ligand.

Rare Earth Oxide Anchored Platinum Catalytic Site Coated Zeolitic Imidazolate Frameworks toward Enhancing Selective Hydrogenation.

Controlling and manipulating the self-assembly technology at the nanoscale has become a powerful strategy for improving chemical processes and further developing the conception of atom efficiency. Herein, an unexpected core-shell structured GdO@Pt@ZIF-8 nanoreactor has been fabricated using the self-assembly strategy in which the firm GdO nanosupport anchored the highly active Pt nanoparticle coated porous zeolitic imidazolate framework (ZIF-8). The well-designed GdO@Pt@ZIF-8 structure shows good performance in selective hydrogenation of aldehyde-, keto-, and nitro-compounds with full conversion (>99.

Heterogeneous Nickel Catalysts Derived from 2D Metal-Organic Frameworks for Regulating the Selectivity of Furfural Hydrogenation.

Hydrolysis of the biomass platform compound furfural can produce a bulk of fine chemicals because of its multiple functional groups. Developing an efficient catalytic system to regulate the process toward some desirable products has always been a hot research area. Herein, the novel Ni-based catalysts (Ni-MFC-, = 300, 400.

Rapid detection of PAH gene mutations in Chinese people.

Background: Phenylketonuria (PKU) is an autosomal recessive genetic disease, caused by the phenylalanine hydroxylase (PAH) deficiency in the metabolic pathway, which prevents phenylalanine from being converted into tyrosine, leading to a large amount of phenylalanine discharged from the urine. Therefore, it is necessary to establish a simple, fast, accurate and reliable PKU molecular diagnostic method for clinical diagnosis.

Methods: We established a novel diagnostic method by combining a single-tube multiplex PCR technique with molecular hybridization technique.

A dual-responsive luminescent metal-organic framework as a recyclable luminescent probe for the highly effective detection of pyrophosphate and nitrofurantoin.

Pyrophosphate (PPi) is a significant biological anion, and its abnormal level in the human body is regarded as a signal of some diseases. Herein, we developed a method for the detection of PPi using a luminescent ZTMOF-1 via the luminescence turn-on effect. PPi formed hydrogen bonds with the phenyl and pyridine rings in the framework, and ZTMOF-1 could discriminately detect PPi among other phosphorus oxides in both an aqueous solution and a physiological environment.

Simultaneous detection of 15 respiratory pathogens with a fluorescence probe melting curve analysis-based multiplex real-time PCR assay.

Acute respiratory tract infections are common worldwide and caused by a great diversity of pathogens. A rapid and accurate diagnosis method of respiratory infection is crucial for timely clinical intervention. Here, by combining fluorescence melting curve analysis and multiplex real-time assay, we developed a novel method which can simultaneously detect 15 respiratory viruses.

A reverse dot blot assay for the screening of twenty mutations in four genes associated with NSHL in a Chinese population.

Background: Congenital deafness is one of the most distressing disorders affecting humanity and exhibits a high incidence worldwide. Most cases of congenital deafness in the Chinese population are caused by defects in a limited number of genes. A convenient and reliable method for detecting common deafness-related gene mutations in the Chinese population is required.

Two novel μ6-O(2-) bridged Co14/Ni14 hydroxamate clusters packed in distorted face-centered cubic patterns.

Two novel clusters [Co(μ6-O(2-))(sbha)12(sba)2 (DMF)7(DMA)]·(DMF)8 (1) and [Ni(μ6-O(2-))(sbha)12(sba)2(DMF)8] (2) (sH2bha = 4-bromo-benzohydroximic acid; sHba = 4-bromobenzene carboxylic acid; DMF = N,N-dimethylformamide; DMA = dimethylamine) have been synthesized. The novel body-centred μ6-O(2-) bridged Co14 and Ni14 clusters are packed in distorted face-centered cubic (FCC) patterns with different symmetries. Magnetic studies confirmed the antiferromagnetic exchange interactions between magnetic centers.

Characterization of Metallosupramolecular Polymers by Top-Down Multidimensional Mass Spectrometry Methods.

Top-down multidimensional mass spectrometry, interfacing electrospray ionization (ESI) with ion mobility mass spectrometry (IM-MS), and energy resolved (gradient) tandem mass spectrometry (gMS(2) ) are employed to characterize the stoichiometries, architectures, and intrinsic stabilities of coordinatively bound supramolecular polymers containing terpyridine functionalized ligands. As a soft ionization method, ESI prevents or minimizes unwanted assembly destruction. The IM dimension affords separation of the supramolecular ions by charge and collision cross-section (a function of size and shape).

Precise Molecular Fission and Fusion: Quantitative Self-Assembly and Chemistry of a Metallo-Cuboctahedron.

Inspiration for molecular design and construction can be derived from mathematically based structures. In the quest for new materials, the adaptation of new building blocks can lead to unexpected results. Towards these ends, the quantitative single-step self-assembly of a shape-persistent, Archimedean-based building block, which generates the largest molecular sphere (a cuboctahedron) that has been unequivocally characterized by synchrotron X-ray analysis, is described.

Towards molecular construction platforms: synthesis of a metallotricyclic spirane based on bis(2,2':6',2"-terpyridine)RuII connectivity.

The design and construction of the first multicomponent stepwise assembly of a -based (tpy=terpyridine), three-dimensional, propeller-shaped trismacrocycle, 8, are reported. Key steps in the synthesis involve the preparation of a hexaterpyridinyl triptycene and its reaction with dimeric, 60°-directional, bisterpyridine-Ru(II) building blocks. Characterization includes ESI- and ESI-TWIM-MS and TEM, along with 1D and 2D (1) H NMR spectroscopy.

Construction of a highly symmetric nanosphere via a one-pot reaction of a tristerpyridine ligand with Ru(II).

A three-dimensional, highly symmetric, terpyridine-based, spherical complex was synthesized via the coordination of four novel, trisdentate ligands and six Ru(2+) ions, and it exhibits excellent stability over a wide range of pH values (1-14). Structural confirmation was obtained by NMR and ESI-TWIM-MS.

A series of rare earth complexes with novel non-interpenetrating 3D networks: synthesis, structures, magnetic and optical properties.

A series of metal-organic framework {Ln(BCPBA)(H2O)}n {Ln = Nd (1), Sm (2), Eu (3), Tb (4), Dy (5)}; {[Ln(BCPBA)(H2O)](H2O)}n {Ln = Pr (6), Gd (7)} have been synthesized through the hydrothermal synthesis method. These compounds possess non-interpenetrating 3D networks with 10.1438 Å× 17.