Fabrication and Analysis of Microcapsule Electrets with a Tunable Flexoelectric-like Response.

The electret has drawn considerable attention as an emerging flexible energy collector. In this work, a charged microcapsule is designed which can provide a stable storage space for electric charge in the electret. The flexoelectric-like response is achieved by embedding a layer of charged microcapsules in the middle plane of the flexible polymer to form an electret.

Enhancing the Electromechanical Coupling in Soft Energy Harvesters by Using Graded Dielectric Elastomers.

Soft dielectric elastomers can quickly achieve large deformations when they are subjected to electromechanical loads. They are widely used to fabricate a number of soft functional devices. However, the functions of soft devices are limited to the failure modes of soft dielectric elastomers.

Nonlinear electromechanical coupling in graded soft materials: Large deformation, instability, and electroactuation.

Subject to an applied electric field, soft dielectrics with intrinsic low moduli can easily achieve a large deformation through the so-called electrostatic Maxwell stress. Meanwhile, the highly nonlinear electromechanical coupling between the mechanical and electric loads in soft dielectrics gives a variety of failure modes, especially pull-in instability. These failure modes make the application of soft dielectrics highly limited.

MicroRNA-21 promotes proliferation in acute myeloid leukemia by targeting Krüppel-like factor 5.

Abnormal expression of microRNA (miR)-21 has been reported in various types of cancers. However, the role and mechanism of miR-21 remain to be elucidated in acute myeloid leukemia (AML). In the present study, it was observed that miR-21 was upregulated and Krüppel-like factor 5 (KLF5) was downregulated in AML cells compared with normal bone marrow cells.

Nonlinear bending deformation of soft electrets and prospects for engineering flexoelectricity and transverse (d) piezoelectricity.

Soft materials that exhibit electromechanical coupling are an important element in the development of soft robotics, flexible and stretchable electronics, energy harvesters, sensor and actuators. Truly soft natural piezoelectrics essentially do not exist and typical dielectric elastomers, predicated on electrostriction and the Maxwell stress effect, exhibit only a one-way electromechanical coupling. Extensive research however has shown that soft electrets i.

Emergent magnetoelectricity in soft materials, instability, and wireless energy harvesting.

Magnetoelectric materials that convert magnetic fields into electricity and vice versa are rare and usually complex, hard crystalline alloys. Recent work has shown that soft, highly deformable magnetoelectric materials may be created by using a strain-mediated mechanism. The electromagnetic and elastic deformation of such materials is intricately coupled, giving rise to a rather rich instability and bifurcation behavior that may limit or otherwise put bounds on the emergent magnetoelectric behavior.

Identifying key genes, pathways and screening therapeutic agents for manganese-induced Alzheimer disease using bioinformatics analysis.

Alzheimer disease (AD) is a progressive neurodegenerative disease, the etiology of which remains largely unknown. Accumulating evidence indicates that elevated manganese (Mn) in brain exerts toxic effects on neurons and contributes to AD development. Thus, we aimed to explore the gene and pathway variations through analysis of high through-put data in this process.

Avoiding the pull-in instability of a dielectric elastomer film and the potential for increased actuation and energy harvesting.

Pull-in instability often occurs when a film of a dielectric elastomer is subjected to an electric field. In this work, we concoct a set of simple, experimentally implementable, conditions that render the dielectric elastomer film impervious to pull-in instability for all practical loading conditions. We show that a uniaxially pre-stretched film has a significantly large actuation stretch in the direction perpendicular to the pre-stretch and find that the maximal specific energy of a dielectric elastomer generator can be increased from 6.