The cutaneous microbiome in skin cancer - A systematic review.

The overall incidence of skin cancer has risen over the past half a decade worldwide and is associated with significant morbidity and mortality. Recent advances in molecular testing have allowed us to better characterize microbiome alterations in skin cancer. However, literature specific to skin microbiome and skin cancer remain heterogenous and scattered.

Metagenomic analysis reveals indole signaling effect on microbial community in sequencing batch reactors: Quorum sensing inhibition and antibiotic resistance enrichment.

Indole is an essential signal molecule in microbial studies. However, its ecological role in biological wastewater treatments remains enigmatic. This study explores the links between indole and complex microbial communities using sequencing batch reactors exposed to 0, 15, and 150 mg/L indole concentrations.

QSP: An open sequence database for quorum sensing related gene analysis with an automatic annotation pipeline.

Quorum sensing (QS) has attracted great attention due to its important role in the bacterial interactions and its relevance to water management. With the development of high-throughput sequencing technology, a specific database for QS-related sequence annotation is urgently needed. Here, Hidden Markov Model (HMM) profiles for 38 types of QS-related proteins were built using a total of 4024 collected seed sequences.

DARHD: A sequence database for aromatic ring-hydroxylating dioxygenase analysis and primer evaluation.

Biodegradation of aromatic compounds is ubiquitous in the environment and important for controlling organic pollutants. Aromatic ring-hydroxylating dioxygenases (ARHDs) are responsible for the first and rate-limiting step of aerobic biodegradation of aromatic compounds. The ARHD α subunit is a good biomarker for studying functional microorganisms in the environment, however their diversity and corresponding primer coverage are unclear, both of which require a comprehensive sequence database for the ARHD α subunit.

Succession of function, assembly, and interaction of microbial community in sequencing biofilm batch reactors under selenite stress.

The mechanism of interaction between selenite, a toxic substance, and the microbial community in wastewater is still not well understood. Herein, nine sequencing biofilm batch reactors were used to systematically investigate the response of the microbial community to the continuous selenite stress. The results showed that selenite affected the reactor performance and reduced the biofilm mass.

Indole metabolism by phenol-stimulated activated sludges: Performance, microbial communities and network analysis.

Indole and phenol often coexist in the coking wastewater, while the effects of phenol on microbial communities of indole metabolism were less explored. In this study, the microbial interactions within activated sludge microbial communities stimulated by indole (group A) or by indole and phenol (group B) were systematically investigated in sequencing batch reactors (SBRs). The results showed that the removal of indole was increased by adding phenol.

Selenium nanoparticles with photocatalytic properties synthesized by residual activated sludge.

The treatment and disposal of residual activated sludge is a worldwide problem and the research on its reuse is still only in the earliest stages. Selenite is a toxic pollutant, while selenium nanoparticles (SeNPs) are environmentally friendly and have promising application prospects. At present, the reduction mechanism of selenite under the complex system is still poorly understood.

Succession of diversity, functions, and interactions of the fungal community in activated sludge under aromatic hydrocarbon stress.

Although fungi are regarded as the important degraders of aromatic hydrocarbons (AHs) in various environments, the dynamic succession and interaction of their community under aromatic hydrocarbon stress has been rarely reported. In this study, we systematically investigated the responses of the fungal community and the associations among fungal species when facing the continuous stress of two typical AHs, benzene and naphthalene. Using high-throughput sequencing technology, we demonstrated that fungal diversity displayed a significant downward trend during six weeks of continuous aromatic hydrocarbon treatment.

Skin conditions in liver transplant recipients in a Singapore academic medical center: A retrospective cohort study.

Background: Liver transplant recipients are at lifelong risk of immunosuppression-related cutaneous complications, such as malignancy and infection.

Objective: Our study aims to assess the epidemiology of dermatologic conditions among liver transplant recipients in an academic medical center in Singapore.

Methods: Medical records of liver transplant recipients on follow-up with gastroenterology and dermatology departments at the Singapore General Hospital between 2006 and 2021 were retrospectively reviewed.

Spectrum of Nail Sequelae in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

This case series documents the incidence of various nail changes as sequalae to Stevens-Johnson syndrome/toxic epidermal necrolysis.

Interaction of graphene-family nanomaterials with microbial communities in sequential batch reactors revealed by high-throughput sequencing.

The accelerated development and application of graphene-family nanomaterials (GFNs) have increased their release to various environments and converged in wastewater treatment plants (WWTPs). However, little is known about the interactions between GFNs and microbes in WWTPs. In this study, the interaction of graphene oxide (GO) or graphene (G) at different concentrations with microbial communities in sequential batch reactors was investigated.

[Characterization of Au-Ag nanoparticles biosynthesized by fungus Mariannaea sp. HJ].

Biosynthesis of gold-silver alloy nanoparticles (Au-AgNPs) is a simple operation and ecological friendly, but with limited reports on the availability of fungal resources. In this study, cell-free extracts of Mariannaea sp. HJ was used to synthesize Au-AgNPs, and the effects of the different ratios of Au and Ag ion concentrations on the synthesis of Au-AgNPs were also studied.

Rod-shaped gold nanoparticles biosynthesized using Pb-induced fungus Aspergillus sp. WL-Au.

Gold nanoparticles (AuNPs) attracted much attention owing to their distinguished characteristics and applications. In this study, rod-shaped AuNPs were biosynthesized using Pb-induced fungus Aspergillus sp. The synthesized AuNPs showed a UV-vis absorption peak at 534 nm.

A rare case of polyarteritis nodosa associated with nontuberculous mycobacterial infection.

Clinicians should be aware that cutaneous PAN can present with significant extracutaneous and constitutional symptoms which make it hard to differentiate from systemic PAN. The condition can also rarely be associated with NTM infections.

Characterization of biogenic selenium nanoparticles derived from cell-free extracts of a novel yeast .

A facile one-pot and effective green process for biogenic selenium nanoparticles (SeNPs) was obtained using the cell-free extracts of a novel yeast LH-F1. The corresponding absorption peak of SeNPs was observed at ~ 560 nm by UV-vis spectrophotometer. In the present study, SeO 2 mM, protein 500 mg L and pH 7 were preferable to the biosynthesis of SeNPs.

Biosynthesis of gold nanoparticles using fungus sp. WL-Go and their catalysis in degradation of aromatic pollutants.

An efficient green method of gold nanoparticles (AuNPs) biosynthesis was achieved by cell-free extracts of fungus sp. WL-Go. Based on UV-Vis spectra, AuNPs biosynthesised by cell-free extracts with 90 mg/l protein exhibited a characteristic absorption band at 556 nm and was stable for 7 days.

Performance and Microbial Community Analysis of Bioaugmented Activated Sludge System for Indigo Production from Indole.

Indole is a typical nitrogen-containing aromatic pollutant in coking wastewater, and it can be used for the microbial production of indigo, one of the oldest dyestuffs. In this study, the activated sludge system bioaugmented with two indigo-producing bacterial strains, wild strain Comamonas sp. MQ and recombinant Escherichia coli (ND_IND), was constructed to investigate indigo bioproduction from indole.