Publications by authors named "Shengxi Xiong"
Article Synopsis
- Polyorchidism is a rare birth condition where a male has more than two testicles, which can negatively affect fertility.
- A case study of a 34-year-old man with this condition revealed severe issues with sperm quality, even though his hormone levels were normal and no genetic problems were found.
- The findings stress the complex link between polyorchidism and male infertility, indicating the need for tailored treatment approaches and more research into its causes and effects.
Background: Long noncoding RNAs (LncRNAs) have been identified to play an important role in diabetes. The aim of the present study was to determine the expression and function of small nucleolar RNA host gene 16 (SNHG16) in diabetic inflammation.
Methods: For the in vitro experiments, quantitative real-time PCR (qRT-PCR), Western blotting and immunofluorescence were used to detect LncRNA SNHG16 expression in the high-glucose state.
Bioinformatics Analysis of the Inflammation-Associated lncRNA-mRNA Coexpression Network in Type 2 Diabetes.
J Renin Angiotensin Aldosterone Syst
March 2023
Introduction: Diabetes is a chronic inflammatory state, and a key role of lncRNAs in diabetes complications is a new area of research.
Methods: In this study, key lncRNAs related to diabetes inflammation were identified by RNA-chip mining and lncRNA-mRNA coexpression network construction and finally verified by RT-qPCR.
Results: We ultimately obtained 12 genes, including A1BG-AS1, AC084125.