Synopsis of recent research by authors named "Shengwen Long"
- Shengwen Long's research primarily focuses on the molecular mechanisms underlying glioma progression and treatment resistance, particularly emphasizing the role of transcription factors like AP-2α in modulating tumor characteristics and immune evasion.
- Recent findings indicate that AP-2α can decrease resistance to temozolomide (TMZ) in recurrent glioblastoma by downregulating MGMT expression and can facilitate immune evasion by upregulating PD-L1 expression in gliomas.
- Long's earlier work also explores the roles of TNFAIP1 as a potential tumor suppressor in hepatocellular carcinoma and developments in methods for identifying miRNA target sites across genomic regions, illustrating a diverse approach to understanding cancer biology.
