Publications by authors named "Shengwei Xiong"

Traumatic ureteral injury is a rare and challenging condition of the urinary system. To summarize the clinical features of patients with traumatic ureteral injury and examine the literature on traumatic ureteral injuries from the past 20 years. The clinical data of 30 patients with traumatic ureteral injury in Peking University First Hospital, Beijing Jiangong Hospital, as well as Emergency General Hospital from August 2015 to August 2023 were retrospectively collected.

View Article and Find Full Text PDF

Background: The aim of this study was to report our technique and medium-term outcomes of modified robot-assisted laparoscopic dismembered pyeloplasty (RALDP) in the Lithotomy Trendelenburg position for treating adult ureteropelvic junction obstruction (UPJO) with horseshoe kidney (HSK).

Methods: Between March 2021 and March 2023, 11 adult patients with UPJO and HSK underwent modified RALDP in the lithotomy Trendelenburg position. Patient demographic characteristics, perioperative parameters, and follow-up outcomes were collected prospectively and analyzed.

View Article and Find Full Text PDF

Urothelial carcinoma (UC) refers to the malignancies originating from transitional epithelium located on the upper and lower urinary tract. Precise diagnosis of UC is crucial since it dictates the treatment efficacy and prognosis of UC patients. Conventional diagnostic approaches of UC mainly fall into four types, including liquid biopsy, imaging examination, endoscopic examination, and histopathological assessment, among others, each of them has contributed to a more accurate diagnosis of the condition.

View Article and Find Full Text PDF
Article Synopsis
  • A new multi-classifier system combines lncRNA, deep learning from whole slide images, and clinicopathological data to improve predictions of recurrence in localized papillary renal cell carcinoma (pRCC) after surgery.
  • *The system shows significantly better predictive accuracy for recurrence-free survival (RFS) than using any single classifier alone, with C-index values ranging from 0.831 to 0.858.
  • *This method helps identify high-risk patients more accurately, allowing for individualized treatment strategies alongside the current cancer staging system.
View Article and Find Full Text PDF

It has become increasingly evident that the structures RNAs adopt are conformationally dynamic; the various structured states that RNAs sample govern their interactions with other nucleic acids, proteins, and ligands to regulate a myriad of biological processes. Although several biophysical approaches have been developed and used to study the dynamic landscape of structured RNAs, technical limitations have limited their application to all classes of RNA due to variable size and flexibility. Recent advances combining chemical probing experiments with next-generation- and direct sequencing have emerged as an alternative approach to exploring the conformational dynamics of RNA.

View Article and Find Full Text PDF

Background: Pelvic lipomatosis (PL) is a rare condition that is characterized by excessive growth of fat in the pelvic cavity. Studies have yet to systematically review surgical treatments for PL.

Objectives: To provide a reference for selecting reasonable surgical treatments for PL patients according to previous literature on the surgical treatment of PL.

View Article and Find Full Text PDF
Article Synopsis
  • * A 44-year-old male patient with a 2.5 cm kidney tumor underwent successful surgery lasting 127 minutes, with no blood loss and a tumor categorized as stage 1a without signs of recurrence after 6 months.
  • * Results indicate that the internal suspension technique is both feasible and effective in rRAPN when utilizing the KD-SR-01 robotic system.
View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates the mid-term outcomes of urological surgeries performed using the new KangDuo-Surgical Robot-01 (KD-SR-01) system at Peking University First Hospital from August 2020 to April 2023.
  • A total of 110 patients underwent various procedures, including partial nephrectomy, urinary tract reconstruction, and radical prostatectomy, with successful outcomes and no major complications reported.
  • The KD-SR-01 system demonstrated feasibility, safety, and effectiveness, suggesting it could be a valuable tool for urological surgeries.
View Article and Find Full Text PDF
Article Synopsis
  • A novel assay was developed to predict recurrence in patients with localised renal cell carcinoma after surgery, integrating clinical, genomic, and histopathological data.
  • A deep learning-based histopathological score was combined with scores from genetic and clinical factors to create a more accurate multimodal recurrence score.
  • This new score showed significantly better predictive accuracy for recurrence-free intervals (RFI) compared to traditional methods, especially identifying high-risk patients, demonstrating its potential for improving patient management post-surgery.
View Article and Find Full Text PDF

To compare the efficacy and safety of robot-assisted laparoscopic radical prostatectomy (RARP) performed using the KangDuo surgical robot system to the da Vinci Si robotic system in clinically localized prostate cancer (KD-RARP DV-RARP). A total of 16 patients underwent extraperitoneal KD-RARP performed by a single experienced surgeon using the KangDuo surgical robot system between May 2021 and August 2021. The data were prospectively collected.

View Article and Find Full Text PDF

Backgrounds: Despite the genomic landscape of urothelial carcinomas (UC) patients, especially those with UC of bladder (UCB), has been comprehensively delineated and associated with pathogenetic mechanisms and treatment preferences, the genomic characterization of upper tract UC (UTUC) has yet to be fully elucidated.

Materials And Methods: A total of 131 Chinese UTUC (74 renal pelvis & 57 ureter) and 118 UCB patients were enrolled in the present study, and targeted next-generation sequencing (NGS) of 618 cancer-associated genes were conducted to exhibit the profile of somatic and germline alterations. The COSMIC database, including 30 mutational signatures, were utilized to evaluate the mutational spectrums.

View Article and Find Full Text PDF

Background and Objectives: To clinically validate the computed tomography (CT)-based three-dimension (3D) model for treatment planning and intraoperative navigation of ureteropelvic junction obstruction (UPJO) complicated with renal calculi. Materials and Methods: We retrospectively collected the data of 26 patients with UPJO and renal calculi who were surgically treated in our institution from January 2019 to December 2021. Before surgery, 3D models based on preoperative CT scans were constructed in all patients.

View Article and Find Full Text PDF

Reactive oxygen species (ROS) are usually produced in rice under aerobic environmental conditions, resulting in peroxidative changes in polyunsaturated fatty acids, and affecting the deterioration of rice during storage. In addition, as an important enzyme that participates in removing ROS, peroxidase is also present in rice, and takes part in protecting rice from attack by ROS. Moreover, loss of peroxidase activity may give rise to rice deterioration during storage.

View Article and Find Full Text PDF

Background: Complete intracorporal robotic ileal ureteric replacement is challenging. We aimed to present the surgical technique of robotic ileal ureter replacement with extracorporeal ileal segment preparation for long ureteral strictures.

Methods: From March 2019 to March 2021, 18 patients underwent robotic ileal ureter replacement with extracorporeal ileal segment preparation by one experienced surgeon.

View Article and Find Full Text PDF

Purpose: Horseshoe kidney (HSK) is the most common renal fusion anomaly, occurring in 0.25% of the population (1). It presents technical obstacles to pyeloplasty for ureteropelvic junction obstruction (UPJO) despite robotic assistance (2, 3).

View Article and Find Full Text PDF

Background: The KangDuo surgical robot (KD-SR) was recently developed in China.

Objective: To compare the safety and efficacy of the KD-SR versus the da Vinci Si Surgical System (DV-SS-Si) for robot-assisted partial nephrectomy (RAPN).

Design, Setting, And Participants: A double-center prospective randomized controlled noninferiority trial of patients aged 18-75 yr with a suspicion of T1a N0M0 renal cancer (RENAL nephrometry score ≤9) was conducted.

View Article and Find Full Text PDF

Purpose: Ureteroplasty with a lingual mucosa graft (LMG) for complex ureteral stricture was reported promising. We aimed to compare outcomes of robotic versus laparoscopic ureteroplasty using a LMG (RU-LMG vs. LU-LMG, respectively).

View Article and Find Full Text PDF

To share our experience in robot-assisted pyeloplasty (RAP) with the Kangduo (KD) surgical robot the da Vinci Si (DV) robotic system (KD-RAP DV-RAP, respectively). From August 2019 to February 2021, 16 patients with ureteropelvic junction obstruction (UPJO) underwent KD-RAP and other 16 patients with UPJO accepted DV-RAP. All procedures were performed by the same surgeon.

View Article and Find Full Text PDF

Purpose: Our goal was to evaluate the feasibility, safety and effectiveness of the KangDuo Surgical Robot-01 (KD-SR-01) system for robot-assisted radical prostatectomy (RARP).

Materials And Methods: This prospective, single-center, single-arm clinical study was conducted from May 2021 to August 2021. Sixteen RARP procedures with the KD-SR-01 system were performed by 1 surgeon.

View Article and Find Full Text PDF

Objective: To analyze the characteristics of ureteral stricture after ureteroscopic holmium laser lithotripsy and summarize our experience with the reconstructive strategies.

Methods: This study retrospectively reviewed 42 patients with ureteral stricture after ureteroscopic holmium laser lithotripsy between December 2009 and December 2019. Patient demographics, laboratory data, imaging studies, perioperative variables, complications, and follow-up data were recorded.

View Article and Find Full Text PDF