Facile fabrication of chitosan/hyaluronic acid hydrogel-based wound closure material Co-loaded with gold nanoparticles and fibroblast growth factor to improve anti-microbial and healing efficiency in diabetic wound healing and nursing care.

Generally, diabetic wounds heal very slowly and inefficiently with an increasing risk of infections. Recent nanotechnology and biomaterial advances elaborate developed multi-functional hydrogels and nanoparticles offer promising solutions to accelerate wound healing for diabetic patients. This research work demonstrates to use of solvent diffusion method to develop hydrogel nanocomposites composed of chitosan (CS), hyaluronic acid (HA), gold (Au), and fibroblast growth factors (FGF).

AKT/GSK-3β signaling is altered through downregulation of mTOR during cerebral Ischemia/Reperfusion injury.

Purpose: Cellular responses following cerebral ischemia/reperfusion injury are critical to recovery and survival after ischemic stroke. Understanding of these cellular responses can help the design of therapies to protect brain tissue and promote recovery after stroke. One of these cellular responses may be mediated by the AKT (protein kinase B) signal transduction pathway.

Sevoflurane-induced neuronal apoptosis in neonatal mice is prevented with intranasal administration of insulin.

Concerns about the potential neurotoxicity of general anesthesia to the developing brain have been increasing in recent years. Animal studies have shown that neonatal exposure to general anesthesia causes both acute neurotoxicity and behavioral abnormalities later in life. In the present study, we observed over-activation of neuronal apoptosis in the brain of neonatal mice after a single exposure to anesthesia with sevoflurane for 6 hours at the age of 7 days.

Intranasal Administration of Insulin Reduces Chronic Behavioral Abnormality and Neuronal Apoptosis Induced by General Anesthesia in Neonatal Mice.

Children, after multiple exposures to general anesthesia, appear to be at an increased risk of developing learning disabilities. Almost all general anesthetics-including sevoflurane, which is commonly used for children-are potentially neurotoxic to the developing brain. Anesthesia exposure during development might also be associated with behavioral deficiencies later in life.

Remediation of petroleum contaminated soils by joint action of Pharbitis nil L. and its microbial community.

The plot-culture experiments were conducted for examining the feasibility of Pharbitis nil L. and its microbial community to remedy petroleum contaminated soils. The petroleum contaminated soil, containing 10% (w/w) of the total petroleum hydrocarbons (TPHs), was collected from the Shengli Oil Field, Dongying City, Shandong Province, China.

Promoted biodegradation and microbiological effects of petroleum hydrocarbons by Impatiens balsamina L. with strong endurance.

Phytoremediation is a promising green technology for cleanup of petroleum hydrocarbons (PHCs) in contaminated environment. Based on the objective of identifying special ornamental plants for the effective biodegradation of PHCs, the efficacy of Impatiens balsamina L. to phytoremedy petroleum contaminated soil from the Shengli Oil Field in Dongying City, Shandong Province, China, was further examined in a field plot-culture experiment under greenhouse conditions.

[Separation performance of 1-microm silica particles as stationary phase for pressurized electrochromatography].

Bare nonporous silica particles with diameter around 1 microm were prepared. A 20 cm section of a total length of 45 cm capillary (100 microm i. d.

Silica spheres coated with C18-modified gold nanoparticles for capillary LC and pressurized CEC separations.

Nonporous monodispersed silica spheres of 1.3 microm were coated with gold nanoparticles (AuNPs) and subsequently coated with n-octadecanethiol. By transmission electron microscopy analysis, the average diameter of the AuNPs on the silica spheres was determined to be 12 nm.

Toxic effects of crude-oil-contaminated soil in aquatic environment on Carassius auratus and their hepatic antioxidant defense system.

Under the indoor simulant conditions, toxic effects of crude-oil-contaminated soil which was put into aquatic environment on the young fishes Carassius auratus and their hepatic antioxidant system after a 20-d exposure were investigated. Results showed that the relationship between the mortality of C. auratus and the exposed doses could be divided into 3 phases: fishes exposed to the low dose groups (0.

Phytoremediation of petroleum contaminated soils by Mirabilis Jalapa L. in a greenhouse plot experiment.

Phytoremediation of soils contaminated by organic chemicals is a challenging problem in environmental science and engineering. On the basis of identifying remediation plants from ornamentals, the remediation capability of Mirabilis Jalapa L. to treat petroleum contaminated soil from the Shengli Oil Field in Dongying City, Shandong Province, China was further investigated using a field plot experiment carried out in a greenhouse.