J Orthop Surg Res
January 2025
Purpose: We aimed to explore the mechanism by which Boron-doped nano-hydroxyapatite (B-nHAp) facilitates the proliferation and differentiation of osteoblasts through controlled release of B.
Methods: B-nHAp characterization was accomplished by means of X-ray diffraction, scanning electron microscopy, inductively coupled plasma mass spectrometry, and transmission electron microscopy. Human bone marrow mesenchymal stem cells (hBMSCs) were subjected to flow cytometry, alizarin red S staining, and cell counting kit-8 assay for proliferation and differentiation determination.
A Mn-based nanozyme, Mn-uNF/Si, with excellent alkali phosphatase-like activity was designed by in-situ growth of ultrathin Mn-MOF on the surface of silicon spheres, and implemented as an effective solid Lewis-Brønsted acid catalyst for broad-spectrum dephosphorylation. HO-mediated GC-MS studies confirmed the cleavage sites and the involvement of HO in the new bonds. DRIFT NH-IR and in-situ ATR-FTIR confirmed the coexistence of Lewis-Brønsted acid sites and the adjustment of adsorption configurations at the interfacial sites.
View Article and Find Full Text PDFLaccase-catalyzed oxidative reactions are increasingly examined as a reliable approach to environmental analysis and remediation, and it is urgent to widen metal category to compensate huge gap in the number of studies on copper- and non-copper laccase mimics. Herein, two-dimensional ultrathin MnO nanofilm (Mn-uNF) was designed via a chemical deposition and alkali etching process. Similar to Cu-laccase, Mn-uNF can oxidize phenols via a one-electron-transfer reaction of Mn(III) and accelerate the Mn/Mn state cycle through an unconventional oxygen reduction process.
View Article and Find Full Text PDFThe treatment of environmental pollutants such as synthetic dyes and lignin has received much attention, especially for biotechnological treatments using both native and artificial metalloenzymes. In this study, we designed and engineered an efficient peroxidase using the O carrier myoglobin (Mb) as a protein scaffold by four mutations (F43Y/T67R/P88W/F138W), which combines the key structural features of natural peroxidases such as the presence of a conserved His-Arg pair and Tyr/Trp residues close to the heme active center. Kinetic studies revealed that the quadruple mutant exhibits considerably enhanced peroxidase activity, with the catalytic efficiency (/) comparable to that of the most efficient natural enzyme, horseradish peroxidase (HRP).
View Article and Find Full Text PDFObjectives: The outbreak of contagious diseases and their associated non-pharmaceutical interventions can lead to negative mental health consequences. This study aimed to investigate online self-compassion exercises' effectiveness in alleviating people's negative affect (anxiety and negative emotions) during the COVID-19 pandemic lockdown.
Methods: Study 1 examined the associations between self-compassion and negative affect using an anonymous online survey.
Organic-inorganic antibacterial materials chitosan@silver/sepiolite (CTs@Ag/Sep) was prepared by grafting organometallic chelate of chitosan and silver on sepiolite. The prepared samples were characterized, and their antibacterial properties were detected. The carrier sepiolite was beneficial for the thermal stability of the composite material.
View Article and Find Full Text PDFUnderstanding the structure-reactivity relationship at the atomic scale is of great theoretical importance for rational design of highly active catalysts, which has long been a central concern in catalysis communities and interface science. Herein, we developed a high-efficiency catalyst for catalytic oxidation of CH by poststructural decoration on well-defined single-crystal facets of hematite. Especially for Cl-decorated {012} facets, the conversion and KA oil selectivity are improved about 3.
View Article and Find Full Text PDFIn this commentary, the author first seeks to counterbalance the current focus on the cost of cultural value mismatch by calling attention to ample evidence in the literature that value mismatch can produce cultural adaptation and resilience in the long run, besides promoting cultural innovations and individual creativity. Second, we propose three factors that differentiate the benefits from the costs of cultural value mismatch. Personal orientation towards integrating heritage and host culture, accurate perception of cultural value differences, and supportive multicultural environments are associated with benefits.
View Article and Find Full Text PDFInt J Geriatr Psychiatry
March 2012
Objective: In China, the rapid socioeconomic transition and the consequential traditional culture change had significant influences on Chinese older-adult depression. In the present study, the prevalence, the potential risk, and the protective factors of depression in the Chinese older population were investigated.
Methods: A cross-sectional survey was conducted with a nationwide representative Chinese sample of 4945 older adults; the Center for Epidemiologic Studies Depression Scale (CES-D) was used as the measurement tool for depressive symptoms.