Application risk and value of Cd-enriched poplar wood: Wood properties, leaching characteristics and brown rot resistance.

This study investigated the application risk and value of Cd-enriched poplar wood, focusing on its wood properties, leaching characteristics, and brown rot resistance. The results indicated that Cd deposition in cell walls significantly inhibited brown rot fungi, thereby enhancing decay resistance. Furthermore, the extent of improvement in brown rot resistance was linked to wood density: the higher the density of Cd-enriched poplar wood, the stronger its resistance to brown rot.

Dynamic job allocation method of multiple agricultural machinery cooperation based on improved ant colony algorithm.

Contemporary large-scale and systematic agricultural operations demand the collaborative efforts of multiple agricultural machines with distinct functionalities. However, the failure of a single agricultural machine during collaborative operations jeopardizes the entire undertaking. To address this challenge, this paper proposes a multi-machine collaborative dynamic job allocation method based on the improved ant colony algorithm.

Combined targeting of Hedgehog/GLI1 and Wnt/β-catenin pathways in mantle cell lymphoma.

Mantle cell lymphoma (MCL) is a rare and aggressive form of non-Hodgkin lymphoma. Challenges in its treatment include relapse, drug resistance, and a short survival period. The Hedgehog/GLI1 (Hh/GLI1) and Wnt/β-catenin pathways are crucial in cancer cell proliferation, survival, and drug resistance, making them significant targets for anticancer research.

Attribution classification method of APT malware based on multi-feature fusion.

In recent years, with the development of the Internet, the attribution classification of APT malware remains an important issue in society. Existing methods have yet to consider the DLL link library and hidden file address during the execution process, and there are shortcomings in capturing the local and global correlation of event behaviors. Compared to the structural features of binary code, opcode features reflect the runtime instructions and do not consider the issue of multiple reuse of local operation behaviors within the same APT organization.

Transfer learning improves predictions in lignin content of Chinese fir based on Raman spectra.

Lignin in biomass plays significant role in substitution of synthetic polymer and reduction of energy expenditure, and the lignin content was usually determined by wet chemical methods. However, the methods' heavy workload, low efficiency, huge consumption of chemicals and use of toxic reagents render them unsuitable for sustainable development and environmental protection. Chinese fir, a prevalent angiosperm tree, holds immense importance for various industries.

[Reversal Effect of NVP-BEZ235 on Doxorubicin-Resistance in Burkitt Lymphoma RAJI Cell Line].

Objective: To study the reversal effect of NVP-BEZ235 on doxorubicin resistance in Burkitt lymphoma RAJI cell line.

Methods: The doxorubicin-resistant cell line was induced by treating RAJI cells with a concentration gradient of doxorubicin. The levels of Pgp, p-AKT, and p-mTOR in cells were detected by Western blot.

The interactions and biological pathways among metabolomics products of patients with coronary heart disease.

Background: Through bioinformatics analysis, this study explores the interactions and biological pathways involving metabolomic products in patients diagnosed with coronary heart disease (CHD).

Methods: A comprehensive search for relevant studies focusing on metabolomics analysis in CHD patients was conducted across databases including CNKI, Wanfang, VIP, CBM, PubMed, Cochrane Library, Nature, Web of Science, Springer, and Science Direct. Metabolites reported in the literature underwent statistical analysis and summarization, with the identification of differential metabolites.

Effects of gas signaling molecule SO in cardiac functions of hyperthyroid rats.

Sulfur dioxide (SO), a novel endogenous gas signaling molecule, is involved in the regulation of cardiac function. Exerting a key role in progression of hyperthyroidism-induced cardiomyopathy (HTC), myocardial fibrosis is mainly caused by myocardial apoptosis, leading to poor treatment outcomes and prognoses. This study aimed to investigate the effect of SO on the hyperthyroidism-induced myocardial fibrosis and the underlying regulatory mechanisms.

How does ultrasound contribute to the migration of extractives inside Ailanthus altissima wood?

Extractives have an impact on the processing and commercial value of wood. Ultrasound is an environmentally friendly technology commonly employed to reduce the extractive content and thus enhance the permeability of wood. This study aimed to understand the migration mechanism of extractives inside wood during ultrasonic treatment, which may help to obtain the desired wood properties.

AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.

Background And Purpose: Research has revealed the involvement of mitochondrial autophagy and iron death in the pathogenesis of myocardial fibrosis. The objective of this study is to investigate whether the mitochondrial-targeted HS donor AP39 inhibits mitochondrial autophagy and antagonizes myocardial cell iron death through the PINK1/Parkin pathway, thereby improving myocardial fibrosis in rats with myocardial infarction.

Experimental Approach: A rat model of myocardial infarction was created by intraperitoneal injection of a high dose of isoproterenol, and H9c2 myocardial cells were subjected to hypoxic injury induced by CoCl.

Information Extraction Network Based on Multi-Granularity Attention and Multi-Scale Self-Learning.

Transforming the task of information extraction into a machine reading comprehension (MRC) framework has shown promising results. The MRC model takes the context and query as the inputs to the encoder, and the decoder extracts one or more text spans as answers (entities and relationships) from the text. Existing approaches typically use multi-layer encoders, such as Transformers, to generate hidden features of the source sequence.

Hydrogen sulfide alleviates hypothyroidism-induced myocardial fibrosis in rats through stimulating autophagy and inhibiting TGF-β1/Smad2 pathway.

Hypothyroidism alone can lead to myocardial fibrosis and result in heart failure, but traditional hormone replacement therapy does not improve the fibrotic situation. Hydrogen sulfide (HS), a new gas signaling molecule, possesses anti-inflammatory, antioxidant, and anti-fibrotic capabilities. Whether HS could improve hypothyroidism-induced myocardial fibrosis are not yet studied.

Gaseous signal molecule SO regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.

Myocardial fibrosis is a key link in the occurrence and development of diabetic cardiomyopathy. Its etiology is complex, and the effect of drugs is not good. Cardiomyocyte apoptosis is an important cause of myocardial fibrosis.

Four new diphenyl ether derivatives from a mangrove endophytic fungus Epicoccum sorghinum.

Four new diphenyl ethers, named epicoccethers K-N (1-4), were purified from the fermentation medium of a fungus Epicoccum sorghinum derived from Myoporum bontioides, and identified through HR-ESI-MS and NMR spectral analysis. Except that compound 1 showed moderate antifungal activity against Penicillium italicum and Fusarium graminearum, the other three compounds showed stronger activity against them than triadimefon. All of them showed moderate or weak antibacterial activity towards Staphylococcus aureus and Escherichia coli with O6 and O78 serotypes except that 3 was inactive to E.

The Metabolomic Characterization of Different Types of Coronary Atherosclerotic Heart Disease in Male.

Background: In clinical practice, many patients with coronary atherosclerotic heart disease (CAD) have atypical clinical symptoms. It is difficult to accurately identify stable CAD or unstable CAD early through clinical symptoms and coronary angiography. This study aimed to screen the potential metabolite biomarkers in male patients with stable CAD and unstable CAD.

Machine learning algorithms for rapid estimation of holocellulose content of poplar clones based on Raman spectroscopy.

In this study, regularization algorithms (RR, LR, and ENR), classical ML algorithms (SVR, DT, and RF), and advanced GBM algorithms (LightGBM, CatBoost, and XGBoost) were applied to build the holocellulose content predictive models of poplar based on features extracted from Raman spectra. Evaluation results of models indicate that classical ML algorithms show higher predictive accuracy than regularization algorithms, and the advanced GBM algorithms better than the classical ML algorithms. Furthermore, models built by CatBoost and XGBoost can estimate holocellulose content with high predictive accuracy of test R above 0.

Machine learning prediction of lignin content in poplar with Raman spectroscopy.

Based on features extracted from Raman spectra, regularization algorithms, SVR, DT, RF, LightGBM, CatBoost, and XGBoost were used to develop prediction models for lignin content in poplar. Firstly, Raman features extracted from FT-Raman spectra after data processing were used as input of models and determined lignin contents were output. Secondly, grid-search combined with cross-validation was used to adjust the hyper-parameters of models.

Novel strategy for establishment of an FT-Raman spectroscopy based quantitative model for poplar holocellulose content determination.

Raman spectroscopy is effective for studying the ultrastructure, lignin content, and cellulose crystallinity of lignocellulosic materials. However, the quantitative analysis of holocellulose in lignocellulosic materials by this technique is challenging. In this study, based on Fourier-transform Raman (FT-Raman) spectroscopy, a novel strategy for building poplar holocellulose content quantitative model was proposed.

New diphenyl ethers from a fungus Epicoccum sorghinum L28 and their antifungal activity against phytopathogens.

The strategy "IEMAHC" (Induction of Endophyte Metabolism by Adding Host Components) was applied to the fermentation of the endophytic fungus Epicoccum sorghinum L28 from Myoporum bontioides by introducing guaiol, an ingredient of M. bontioides, into the cultivation medium, which resulted in the purification of nine new diphenyl ethers, epicoccethers A-I (1-9). Their structures were determined by overall spectroscopic analysis.

Predictive Modeling of Lignin Content for the Screening of Suitable Poplar Genotypes Based on Fourier Transform-Raman Spectrometry.

The quick and non-invasive evaluation of lignin from biomass has been the focus of much attention. Several types of spectroscopies, for example, near-infrared (NIR) and Fourier transform-Raman (FT-Raman), have been successfully applied to build quantitative predictive lignin models based on chemometrics. However, due to the effect of sample moisture content and ambient humidity on its signals, NIR spectroscopy requires sophisticated pre-testing preparation.

APDL1-CART cells exhibit strong PD-L1-specific activity against leukemia cells.

Chimeric antigen receptor (CAR) T cells target specific tumor antigens and lyse tumor cells in an MHC-independent manner. However, the efficacy of CAR-T cell and other cancer immunotherapies is limited by the expression of immune-checkpoint molecules such as programmed death-ligand 1 (PD-L1) on tumor cells, which binds to PD-1 receptors on T cells leading to T cell inactivation and immune escape. Here, we incorporated a PD-L1-targeted single-chain variable fragment (scFv) fusion protein sequence into a CAR vector to generate human anti-PD-L1-CAR-T cells (aPDL1-CART cells) targeting the PD-L1 antigen.

Photocatalytic Degradation of Tetracycline by a Novel (CMC)/MIL-101(Fe)/β-CDP Composite Hydrogel.

Herein, we report a novel carboxymethyl cellulose (CMC)/MIL-101 (Fe)/poly(β-cyclodextrin) (β-CDP) hydrogel with high photocatalytic activity. β-CDP can significantly enhance the photoactivity of MIL-101(Fe) in the hydrogel prepared by a simple solvothermal method. The structure and property of this composite hydrogel were characterized by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy.

Calreticulin increases growth and progression of natural killer/T-cell lymphoma.

In this study, we investigated the role of calreticulin (CALR) in the pathogenesis of natural killer/T-cell lymphoma (NKTCL). CALR expression was significantly higher in the NKTCL tissues than normal control tissues in the GSE80632 dataset. High CALR expression correlated with poorer overall survival of NKTCL patients ( = 0.

Low Water Absorption, High-Strength Polyamide 6 Composites Blended with Sustainable Bamboo-Based Biochar.

To promote the application of polyamide 6 (PA6) in wood-plastic composites, the negative effects associated with the thermal degradation of plant fibers must be overcome. In this study, waste bamboo fibers were subjected to pyrolysis and ball milling to afford nano bamboo-based biochar (BC), which was subsequently used as reinforcement to prepare PA6/BC nano composites by injection molding. In addition, the processing fluidity, water absorption, mechanical properties, and interface compatibility of PA6/BC composites were discussed.

Hemicelluloses-based magnetic aerogel as an efficient adsorbent for Congo red.

A renewable, efficient, and low-cost material is essential for adsorbing water pollution, such as dyes and heavy metal ions pollution. Here in, we demonstrate an aerogel to remove the dyes from water based on hemicellulose. The dialdehyde hemicelluloses (DAH) were synthesized by oxidation of hemicellulose extracted from straw with NaIO.