Publications by authors named "Shengming Shi"
Article Synopsis
- The study focuses on developing the best prediction model for liver metastasis in rectal cancer, aiming to assist doctors with early diagnosis and treatment decisions.
- A total of 193 patients were analyzed, with predictive models created from clinical data and radiomics features derived from MRI scans, highlighting the importance of KRAS mutations as a key indicator for metastasis.
- The combined prediction model outperformed individual models, showing higher accuracy in identifying liver metastasis in both training and validation sets.
Cancer is a leading cause of mortality globally, characterized by intricate molecular alterations, including epigenetic changes such as glycosylation. This study presents a comprehensive pan-cancer analysis of Polypeptide N-Acetylgalactosaminyltransferase 7 (GALNT7), an enzyme involved in mucin-type O-linked protein glycosylation. GALNT7 has previously been linked to various cancers, but a unified analysis across cancer types is lacking.
View Article and Find Full Text PDFBackground: Recently, the impact of fine particulate matter pollution on cardiovascular system is drawing considerable concern worldwide. The association between ambient fine particulate and the cardiac arrhythmias is not clear now.
Objective: To study associations of ambient fine particulate with incidence of arrhythmias in outpatients.
Article Synopsis
- The study aimed to identify hypoglycemic components from acid hydrolyzates of total saponins and assess their effectiveness in inhibiting α-glycosidase enzymes and PTP1B.
- Researchers purified eight compounds using silica gel chromatography and identified their structures through NMR, finding that one compound was previously unreported.
- Some isolated compounds showed strong inhibitory effects, particularly one with an IC value significantly lower than the control for α-glucosidase, suggesting potential use as a functional anti-diabetic agent.
Four new dammarane-type triterpene saponins, 1-4, were isolated from the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino. Their structural elucidations were accomplished mainly on the basis of spectroscopic methods, such as IR, HR-TOF-MS, and NMR.
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