Serpin B9 is Highly Expressed in Lung Adenocarcinoma and is Associated with Progression-Free Survival.

Background: Serpin B9 is highly expressed in breast cancer, melanoma, and various malignant cells and inhibits NK cell killing through the Serpin B9-GrB axle. However, the current studies have only validated the role of Serpin B9 in vivo and vitro, and lack of systematic studies on the expression of Serpin B9 in patients' tumor tissues and its prognostic implications. In this study, we propose to further validate the role of Serpin B9 by comparing its expression level in tissues of lung adenocarcinoma patients and its correlation with the efficacy of immunotherapy.

A Case-Control Study of the Relationship Between Genetic Polymorphism and Cretinism in Xinjiang.

Background: Cretinism is a subtype of congenital hypothyroidism, an endocrine disorder resulting from inadequate thyroid hormone production or receptor deficiency. Genetic abnormalities play a major role in the development of thyroid dysfunction.

Methods: We recruited 183 participants with cretinism and 119 healthy participants from the Xinjiang Uyghur Autonomous Region and randomly selected 29 tag single nucleotide polymorphisms (tSNPs) in , and in all participants.

Big data analysis for evaluating bioinvasion risk.

Background: Global maritime trade plays an important role in the modern transportation industry. It brings significant economic profit along with bioinvasion risk. Species translocate and establish in a non-native area through ballast water and biofouling.

Reputation-Aware Recruitment and Credible Reporting for Platform Utility in Mobile Crowd Sensing with Smart Devices in IoT.

The Internet of things (IoT) comprises a huge collection of electronic devices connected to the Internet to ensure the dependable exchange of sensing information. It involves mobile workers (MWs) who perform various activities to support enormous online services and applications. In mobile crowd sensing (MCS), a massive amount of sensing data is also generated by smart devices.

Social Welfare Control in Mobile Crowdsensing Using Zero-Determinant Strategy.

As a promising paradigm, mobile crowdsensing exerts the potential of widespread sensors embedded in mobile devices. The greedy nature of workers brings the problem of low-quality sensing data, which poses threats to the overall performance of a crowdsensing system. Existing works often tackle this problem with additional function components.

Context Sensing System Analysis for Privacy Preservation Based on Game Theory.

In a context sensing system in which a sensor-equipped mobile phone runs an unreliable context-aware application, the application can infer the user's contexts, based on which it provides personalized services. However, the application may sell the user's contexts to some malicious adversaries to earn extra profits, which will hinder its widespread use. In the real world, the actions of the user, the application and the adversary in the context sensing system affect each other, so that their payoffs are constrained mutually.