Hypothetical Protein VDAG_07742 Is Required for Pathogenicity in Potato.

is a soil-borne pathogenic fungus that causes Verticillium wilt in host plants, a particularly serious problem in potato cultivation. Several pathogenicity-related proteins play important roles in the host infection process, hence, identifying such proteins, especially those with unknown functions, will surely aid in understanding the mechanism responsible for the pathogenesis of the fungus. Here, tandem mass tag (TMT) was used to quantitatively analyze the differentially expressed proteins in during the infection of the susceptible potato cultivar "Favorita".

MicroRNA-381 Negatively Regulates TLR4 Signaling in A549 Cells in Response to LPS Stimulation.

It is widely reported that miR-381 is dysregulated in various tumors. However, the specific role of miR-381 in respiratory infections has not been reported. To probe this role, A549 cells were pretreated with 1 μg/mL LPS for 24 h.

A case study of imported pulmonary coccidioidomycosis.

Coccidioidomycosis is an endemic disease of the Western hemisphere. The cases in non-endemic areas are mostly imported. Determining a history of exposure is critical for performing the diagnosis of coccidioidomycosis, especially for cases occurring in a non-endemic area.

[Clinical characteristics of 8 cases of primary tracheal tumors].

Objective: To explore the clinical characteristics of primary tracheal tumors and therefore to improve the diagnosis and treatment.

Methods: A retrospective analysis of the clinical data of 8 patients with primary tracheal tumors admitted to our department during the period of May 1994 to May 2006 was performed, with detailed description of the clinical manifestations, chest radiography, fiberoptic bronchoscopy, lung function measurements, treatment and prognosis for 4 cases.

Results: Seven patients presented with irritable cough and progressive inspiratory dyspnea, mostly misdiagnosed as asthma or chronic bronchitis.

[Large-volume whole lung lavage in the treatment of severe pulmonary alveolar proteinosis].

Objective: To evaluate the efficacy and safety of large-volume whole lung lavage in the treatment of severe pulmonary alveolar proteinosis (PAP).

Methods: Five severe PAP patients underwent large-volume whole lung lavage under general anaesthesia using a double lumen endotracheal tube. Suction was used for returning fluid.