Demonstration of high-speed and low-complexity continuous variable quantum key distribution system with local local oscillator.

We present an experimental demonstration of the feasibility of the first 20 + Mb/s Gaussian modulated coherent state continuous variable quantum key distribution system with a locally generated local oscillator at the receiver (LLO-CVQKD). To increase the signal repetition rate, and hence the potential secure key rate, we equip our system with high-performance, wideband devices and design the components to support high repetition rate operation. We have successfully trialed the signal repetition rate as high as 500 MHz.

Secure optical communication using a quantum alarm.

Optical fibre networks are advancing rapidly to meet growing traffic demands. Security issues, including attack management, have become increasingly important for optical communication networks because of the vulnerabilities associated with tapping light from optical fibre links. Physical layer security often requires restricting access to channels and periodic inspections of link performance.

Cyclin C/cdk3 promotes Rb-dependent G0 exit.

G0 is a physiological state occupied by resting or terminally differentiated cells that have exited the cell cycle. In contrast to the well-characterized cyclin/cdk-mediated inactivation of pRb that controls the G1/S transition, little is known about regulation of the G0/G1 transition. However, pRb is likely to participate in this process because its acute somatic inactivation is sufficient for G0-arrested cells to re-enter the cell cycle.

Depletion of wild-type huntingtin in mouse models of neurologic diseases.

Huntington's disease (HD) is caused by a mutation in the gene encoding for huntingtin resulting in selective neuronal degeneration. Because HD is an autosomal dominant disorder, affected individuals have one copy of the mutant and one copy of the wild-type allele. Huntingtin has antiapoptotic properties and is critical for cell survival.