Graefes Arch Clin Exp Ophthalmol
December 2024
Purpose: To characterize the clinical features of macular neovascularization (MNV) secondary to Bietti crystalline dystrophy.
Methods: The imaging data of 157 eyes in 79 patients with Bietti crystalline dystrophy were retrospectively reviewed. 12 individuals (19 eyes) were found to have MNVs.
Comput Methods Programs Biomed
February 2023
Background And Objectives: Automated diagnosis using deep neural networks can help ophthalmologists detect the blinding eye disease wet Age-related Macular Degeneration (AMD). Wet-AMD has two similar subtypes, Neovascular AMD and Polypoidal Choroidal Vasculopathy (PCV). However, due to the difficulty in data collection and the similarity between images, most studies have only achieved the coarse-grained classification of wet-AMD rather than a fine-grained one of wet-AMD subtypes.
View Article and Find Full Text PDFBackground: Lipemia retinalis (LR) is a rare disease related to hypertriglyceridemia. However, the symptoms of hypertriglyceridemia are insidious and difficult to detect without blood tests. The fundus is the only site where blood vessels can be observed directly.
View Article and Find Full Text PDFEvid Based Complement Alternat Med
June 2022
Objective: To investigate the relationship between vascular endothelial growth factor-C (VEGF-C) and tumor-associated macrophages in oral cancer (TAMs) with lymph node metastasis.
Method: From January 2018 to January 2022, 155 cases of oral cancer tissues and 165 cases of normal mucosal tissues were collected from oral surgical resection tissues or biopsy specimens in Hebei Eye Hospital. Oral cancer tissues were observed.
Objective: The aim of the study is to observe the difference in progression between type 1 and type 2 Bietti crystalline dystrophy (BCD) using multimodal imaging.
Methods: A retrospective clinical study was performed with six BCD patients who underwent multimodal imaging twice in Hebei Provincial Eye Hospital from October 2015 to December 2020. Multimodal imaging includes color fundus photography, fundus autofluorescence (AF), infrared autofluorescence (IRAF), fundus fluorescein angiography (FFA), and spectral domain optical coherence tomography (SD-OCT).
Comput Methods Programs Biomed
November 2021
Background And Objectives: Deep learning algorithms show revolutionary potential in computer-aided diagnosis. These computer-aided diagnosis techniques often rely on large-scale, balanced standard datasets. However, there are many rare diseases in real clinical scenarios, which makes the medical datasets present a highly imbalanced long-tailed distribution, leading to the poor generalization ability of deep learning models.
View Article and Find Full Text PDFBackground: Bietti crystalline dystrophy (BCD) is an autosomal recessive genetic disorder that causes progressive vision loss. Here, 12 patients were followed up for 1-5 years with fundus fluorescein angiography (FFA) to observe BCD disease progression.
Methods: FFA images were collected for 12 patients with BCD who visited our clinic twice or more over a 5-year period.
Purpose: The aim of this study was to measure and compare the retinal vascular parameters and foveal avascular zone (FAZ) in Chinese and Caucasian populations by using optical coherence tomography angiography (OCT-A).
Methods: Fifty-one eyes of Han Chinese and 43 eyes of Caucasians were retrospectively included in our study. The measurements were acquired using Zeiss Cirrus 5000, with the same software version 10 in Poland and China.
Aim: To explore the effect of Obtusifolin on retinal pigment epithelial cell growth under hypoxia.
Methods: chemical hypoxia model of ARPE-19 cells was established using cobalt chloride (CoCl). Cell viability was tested by cell counting kit-8 (CCK-8) assay.
Vitrectomy combined with internal limiting membrane peeling (ILMP) treats high myopic foveoschisis with good results, but there is a risk of iatrogenic macular holes, which may be reduced by preserving the internal limiting membrane of the central fovea. This study compared complete ILMP with partial ILMP, both combined with 25G vitrectomy, for the treatment of high myopic foveoschisis.Thirty-three cases (33 eyes) of high myopic foveoschisis were retrospectively analyzed.
View Article and Find Full Text PDFObjective: To study the inhibition effect of Salvinia natans ( L. ) All. on harmful algae.
View Article and Find Full Text PDFObjective: To study the inhibiting effect of aquaculture water of Salvinia natans (L.) All. on Microcystis aeruginosa and the mechanism.
View Article and Find Full Text PDFObjective: To study the inhibition effect on blue-green algae of higher aquatic plants with their rhizosphere microorganisms and its mathematical model.
Methods: The inhibitory effects of sterile and containing bacterium Myriophyllum verticillatum L root extracts on Microcystis aeruginosa were studied respectively, and the difference-differential equation of algal growth and partial functional differential equation were established according to the algal inhibiting effect.
Results: (1) The sterile and containing bacterium Myriophyllum verticillatum L root extracts showed at some degree inhibitory effects on M.
Objective: To study the variation of polysaccharide (PS), which can be classified as capsule polysaccharide (EPS) and extracellular polysaccharide (EPS), and microcystin-RR (MC-RR) content of Microsystis aeruginosa under the stress of salicylic acid (SA).
Methods: 0, 0.25, 0.