Curr Issues Mol Biol
September 2024
In order to understand the bias and main affecting factors of codon usage in the plastid genome of , which is a rare and endangered plant species in the Orchidaceae family, the complete plastid genome sequence of was downloaded from the GenBank database and 20 protein-coding sequences that met the analysis requirements were finally selected. The GC content, length of the amino acid (Laa), relative synonymous codon usage (RSCU), and effective number of codon (ENC) of each gene and codon were calculated using the CodonW and EMBOSS online programs. Neutral plot analysis, ENC-plot analysis, PR2-plot analysis, and correspondence analysis were performed using Origin Pro 2024 software, and correlation analysis between various indicators was performed using SPSS 23.
View Article and Find Full Text PDFThe Soret effect is a significant factor in various scenarios, with thermodiffusion in binary systems serving as a common method for the study. Most research focuses rarely on the distribution characteristics of components in diffusion systems; and Soret coefficients in the porous media could not be obtained by typical methods based on the thermodiffusion column, which are particularly important in the field of oil and gas development. Moreover, experiments on ground conditions have struggled to determine the Soret coefficient accurately due to the convective effect caused by gravity differentiation.
View Article and Find Full Text PDFAs urban development accelerates and natural disasters occur more frequently, the urgency of developing effective emergency shelter planning strategies intensifies. The shelter location selection method under the traditional multi-criteria decision-making framework suffers from issues such as strong subjectivity and insufficient data support. Artificial intelligence offers a robust data-driven approach for site selection; however, many methods neglect the spatial relationships of site selection targets within geographical space.
View Article and Find Full Text PDFNanomaterials (Basel)
February 2024
Tuning the lattice spacing or stop bands holds great significance in the design and application of materials with colloidal crystals. Typically, particle surface modifications or the application of external physical fields are needed. In this study, we demonstrated the ability to expand or compress the lattice of colloidal crystals simply by utilizing a salt solution, without the need for any special treatments to the colloidal particles.
View Article and Find Full Text PDFBy using a large enough number of particles and implementing a parallel algorithm on the CUDA platform, we have performed brute-force molecular dynamics simulations to study the template-induced heterogeneous crystallization in charged colloids. Six kinds of templates, whose patterns include the planes of fcc(100), fcc(110), fcc(111), bcc(100), bcc(110) and bcc(111), have been implanted into the middle of the simulation box. Except the fcc(111) template, whose structure benefits not only fcc but also hcp crystals resulting in a similar behavior to homogeneous crystallization, bcc-type templates favor the formation of bcc crystals and bcc-like precursors while fcc-type templates favor the formation of fcc crystals and fcc-like precursors.
View Article and Find Full Text PDFElectrically pumped halide perovskite laser diodes remain unexplored, and it is widely acknowledged that continuous-wave (CW) lasing will be a crucial step. Here, we demonstrate room-temperature amplified spontaneous emission of Fe-doped CsPbBr crystal microwire excited by a CW laser. Temperature-dependent photoluminescence spectra indicate that the Fe dopant forms a shallow level trap states near the band edge of the lightly doped CsPbBr microcrystal.
View Article and Find Full Text PDFBackground: Glutamine (Gln) metabolism has been confirmed as an important fuel in cancer metabolism. This study aimed to uncover potential links of Gln with long non-coding RNAs (lncRNAs) and the prognostic value of Gln-associated lncRNAs in multiple myeloma (MM) patients.
Methods: The RNA-seq expression profile and corresponding clinical data of gastric cancer obtained from Gene Expression Omnibus (GEO) database.
Halide perovskites are increasingly exploited as semiconducting materials in diverse optoelectronic applications, including light emitters, photodetectors, and solar cells. The halide perovskite can be easily processed in solution, making microfluidic synthesis possible. This review introduces perovskite nanostructures based on micron fluidic channels in chemical reactions.
View Article and Find Full Text PDFThere is a critical need for detection of administrative regions through network map pictures in map censorship tasks, which can be implemented by target detection technology. However, on map images there tend to be numerous administrative regions overlaying map annotations and symbols, thus making it difficult to accurately detect each region. Using a RetinaNet-based target detection model integrating ResNet50 and a feature pyramid network (FPN), this study built a multi-target model and a single-target cascading model from three single-target models by taking Taiwan, Tibet, and the Chinese mainland as target examples.
View Article and Find Full Text PDFMolecular dynamics is employed to simulate the Soret effect on two binary liquid solutions with equimolar mixtures: normal pentane (-pentane, nC-5) and normal heptane (-heptane, nC-7) molecules plus normal decane (-decane, nC-10) and normal pentane molecules. Moreover, two coarse-grained force field (the CG-FF) potentials, which may depict inter-/intramolecular interactions fairly well among -alkane molecules, are developed to fulfill such investigations. In addition, thermal diffusion for the mass fraction of each of these -alkane molecules is simulated under an effect of a weak thermal gradient (temperature difference) exerting on solution systems from their hot to cold boundary sides.
View Article and Find Full Text PDFWe present the Topical Issue 'Diffusion and Convection in Nature'.
View Article and Find Full Text PDFExtranodal natural killer/T-cell lymphoma, nasal-type (ENKTL) is a distinct subtype of non-Hodgkin lymphoma and most of the patients presented localized disease. Combined modality therapy (CMT), namely chemotherapy combined with radiotherapy, has been recommended for patients with early-stage ENKTL. However, the optimal CMT has not been fully clarified.
View Article and Find Full Text PDFAs a key algorithm in bioinformatics, sequence alignment algorithm is widely used in sequence similarity analysis and genome sequence database search. Existing research focuses mainly on the specific steps of the algorithm or is for specific problems, lack of high-level abstract domain algorithm framework. Multiple sequence alignment algorithms are more complex, redundant, and difficult to understand, and it is not easy for users to select the appropriate algorithm; some computing errors may occur.
View Article and Find Full Text PDFAfter years of development, the complexity of the biological sequence alignment algorithm is gradually increasing, and the lack of high abstract level domain research leads to the complexity of its algorithm development and improvement. By applying the idea of software components to the design and development of algorithms, the development efficiency and reliability of biological sequence alignment algorithms can be effectively improved. The component assembly platform applies related assembly technology, which simplifies the operation difficulty of component assembly and facilitates the maintenance and optimization of the algorithm.
View Article and Find Full Text PDFWe investigated the evolution of concentration and phase structure of colloidal suspensions in a two-ends-open tube during drying process. The volume fraction and crystal structure of suspension in the capillary tube were determined by reflection spectrometer during drying process. Our experimental results show: (a) evaporation takes place in two directions of the tube, though much stronger in one direction than the other; (b) during drying process, colloidal suspension column along the tube can be divided into four regions, namely, the close packed region, concentrated region, initial concentration region and dilution region.
View Article and Find Full Text PDFBy using a graphics processing unit-accelerated parallel algorithm on a compute unified device architecture platform, we perform large-scale molecular dynamics simulations in a Lennard-Jones system to observe the entire crystallization process, including metastable stage, critical nuclei formation, and the stage of crystal growth. Although the intermediated precursors that play a role in determining the polymorphs are predominantly bcc ordered, the polymorph selection is rather different at different stages. The precursors that have a relatively high orientational order will be on average in a denser region than uniform liquids, but microscopically the crystal nucleation happens without a density change.
View Article and Find Full Text PDFIn this study, bulk modulus of a colloidal crystal formed by highly charged particles is experimentally determined by applying direct current electric field. A theoretical expression is also proposed to independently predict the bulk modulus based on van't Hoff's law of osmotic pressure and the theory of Ohshima. The experimental result thus obtained agrees well with the theoretical expectation.
View Article and Find Full Text PDFUnderstanding the molecular mechanisms for the development of non-Hodgkin lymphoma (NHL) will improve our ability to cure the patients. qRT-PCR was applied for the examination of the efficiency of shRNA for DNMT1, the expression of suppressor genes, miRNA-152. The MTT analysis, cell cycle analysis, clonal formation, and apoptotic analysis were used to examine the functions of DNMT1 and miR-152 in lymphoma cells.
View Article and Find Full Text PDFThe dynamic process of homogenous nucleation in charged colloids is investigated by brute-force molecular dynamics simulation. To check if the liquid-solid transition will pass through metastable bcc, simulations are performed at the state points that definitely lie in the phase region of thermodynamically stable fcc. The simulation results confirm that, in all of these cases, the preordered precursors, acting as the seeds of nucleation, always have predominant bcc symmetry consistent with Ostwald's step rule and the Alexander-McTague mechanism.
View Article and Find Full Text PDFPorous microcarriers have aroused increasing attention recently, which can create a protected environment for sufficient cell seeding density, facilitate oxygen and nutrient transfer, and well support the cell attachment and growth. In this study, porous microcarriers fabricated from the strontium-substituted hydroxyapatite- graft-poly(γ-benzyl-l-glutamate) (Sr10-HA- g-PBLG) hybrid nanocomposite were developed. The surface grating of PBLG, the micromorphology and element distribution, mechanical strength, in vitro degradation, and Sr ion release of the obtained Sr10-HA- g-PBLG porous microcarriers were investigated, respectively.
View Article and Find Full Text PDFThe microcarrier system offers an attractive method for cellular amplification and phenotype enhancement in the field of bone tissue engineering. However, it remains a challenge to fabricate porous microcarriers with osteoinductive activity for speedy and high-quality osseointegration in regeneration of serious complication of bone fracture, like nonunion. Here, we present a facile method for the first time manufacture microcarriers with osteogenic effects and properties based on well controlled and long-term Sr release.
View Article and Find Full Text PDFCompositional grading within a mixture has a strong impact on the evaluation of the pre-exploitation distribution of hydrocarbons in underground layers and sediments. Thermodiffusion, which leads to a partial diffusive separation of species in a mixture due to the geothermal gradient, is thought to play an important role in determining the distribution of species in a reservoir. However, despite recent progress, thermodiffusion is still difficult to measure and model in multicomponent mixtures.
View Article and Find Full Text PDFThe crystallization process of Hertzian spheres is studied by means of molecular dynamics simulations in an NPT ensemble where the total number of particles N, the pressure P, and the temperature T are kept constant. It has been observed that the bond orientational ordering rather than the translational ordering (density) plays a primary role. The crystal polymorphs are determined by the state points.
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