Publications by authors named "Shenghan Cai"
Transition metal-catalyzed enantioconvergent cross-coupling of an alkyl precursor presents a promising method for producing enantioenriched C(sp) molecules. Because alkyl alcohol is a ubiquitous and abundant family of feedstock in nature, the direct reductive coupling of alkyl alcohol and aryl halide enables efficient access to valuable compounds. Although several strategies have been developed to overcome the high bond dissociation energy of the C - O bond, the asymmetric pattern remains unknown.
View Article and Find Full Text PDFBackground: During the early "containment" phase of the COVID-19 response in England (January-March 2020), contact tracing was managed by Public Health England (PHE). Adherence to self-isolation during this phase and how people were making those decisions has not previously been determined. The aim of this study was to gain a better understanding of decisions around adherence to self-isolation during the first phase of the COVID-19 response in England.
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- The UK Government's national shielding program during the COVID-19 pandemic aimed to protect clinically extremely vulnerable (CEV) individuals by advising them to stay at home and limit contact.
- A mixed methods study, including surveys and interviews, was conducted with individuals in Southwest England identified as CEV to evaluate the impact of shielding on their health and wellbeing.
- Results showed that while many felt they received adequate advice, the timing and clarity of communication were criticized, and a significant proportion reported worsened physical and mental health, with notable concerns about depression and anxiety levels.
Article Synopsis
- Antibiotic resistance poses a serious global health threat, particularly affecting low-income populations in less-developed countries, necessitating comprehensive research across various fields.
- This study focuses on documenting human exposure to antibiotics and health outcomes using a mixed-methods approach in rural China, incorporating microbiological, genomic, and sociological perspectives.
- Through extensive data collection and analysis, the research aims to identify antibiotic resistance patterns, the drivers of antibiotic use, and to propose effective policies for managing antibiotic practices in the region.
Background: Evidence highlights the disproportionate impact of measures that have been introduced to reduce the spread of coronavirus on individuals from Black, Asian and minority ethnic (BAME) communities, and among those on a low income. An understanding of barriers to adherence in these populations is needed. In this qualitative study, we examined the patterns of adherence to mitigation measures and reasons underpinning these behaviors.
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