Publications by authors named "ShengZhe Zhou"
Article Synopsis
- Programmed cell death (PCD) pathways are crucial for understanding the development and progression of lung adenocarcinoma (LUAD), serving as effective prognostic markers and influencing drug sensitivity.
- Through single-cell analysis and a machine learning approach, a PCD-related signature (PCDS) was created that outperformed existing models in predicting patient outcomes, allowing for stratification into high-risk and low-risk groups based on overall survival rates.
- The study also highlighted significant differences in the tumor microenvironment and drug sensitivity between the risk groups, with findings confirming the role of specific PCD-associated genes in LUAD cell behavior, ultimately aiding in prognosis and treatment strategies for patients.
Radiofrequency Improves Facial Fine Lines by Thermal Effect: Damage or Just Stimulation?
J Cosmet Dermatol
September 2024
Background: Radiofrequency (RF) has been widely used for rejuvenation treatments, but without knowledge of the effective temperature of the target tissues or guidance on treatment parameters, it often leads to adverse reactions and pain. The aim of this study was to demonstrate that thermal stimulation can produce facial rejuvenation effects and to determine the optimal bipolar RF treatment parameters for treating facial fine lines.
Methods: A bipolar RF device combined with CORE Technology was used in this study.
Objectives: Subsegmentectomy has been adopted for non-small cell lung cancer (NSCLC) for decades. This study aimed to compare the features between subsegmentectomy, segmentectomy and wedge resection for NSCLC.
Materials And Methods: NSCLC patients who underwent subsegmentectomy, segmentectomy, or wedge resection between 2014 and 2019 were retrospectively screened.
Bacterial infections and excessive inflammation present substantial challenges for clinical wound healing. Hydrogels with mild photothermal (PTT) effects have emerged as promising agents owing to their dual actions: positive effects on cells and negative effects on bacteria. Here, an injectable self-healing hydrogel of oxidized konjac glucomannan/arginine-modified chitosan (OKGM/CS-Arg, OC) integrated with protocatechualdehyde-@Fe (PF) nanoparticles capable of effectively absorbing near-infrared radiation is synthesized successfully.
View Article and Find Full Text PDFStaphylococcus aureus (Sau) plays an important role in human infections occurring in both the community and hospital settings. Sau-related chronic and relapsing infections are mainly attributed to small-colony variants (SCVs), a type of subpopulation that has a size one-tenth that of normal colonies and is accompanied by several unique characteristics, including a lack of or reduced pigmentation, decreased hemolytic activity, increased biofilm formation, enhanced resistance to antimicrobials, upregulated genes encoding adhesion molecules, and downregulated genes for virulence factors. This review summarizes the significance of genetic mutations involved in diverse biosynthesis pathways that contribute to Sau-SCV promotion.
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