TREM2 alleviates white matter injury after traumatic brain injury in mice might be mediated by regulation of DHCR24/LXR pathway in microglia.

Background: White matter injury (WMI) is an important pathological process after traumatic brain injury (TBI). The correlation between white matter functions and the myeloid cells expressing triggering receptor-2 (TREM2) has been convincingly demonstrated. Moreover, a recent study revealed that microglial sterol metabolism is crucial for early remyelination after demyelinating diseases.

Comprehensive effect of increased calcium content in coal on the selenium emission from coal-fired power plants: Combined laboratory and field experiments.

Coal combustion is the major contributor to global toxic selenium (Se) emissions. Inorganic elements in coals significantly affect Se partitioning during combustion. This work confirmed that the calcium (Ca) in ash had a stronger relationship with Se retention at 1300 °C than other major elements.

Diagnosis and comprehensive treatment of a glucagonoma in a patient with residual intrahepatic metastases postoperatively: A case report and literature review.

Glucagonomas are rare neuroendocrine neoplasms of the pancreas with malignant potential. At present, their epidemiology is not entirely clear, so clinicians are not well versed, lacking any consensus on diagnosis or comprehensive treatment. The present study reports the case of a 32-year-old woman hospitalized for recurrent glossitis, perioral dermatitis and necrolytic migratory erythema (NME) of both lower limbs.

Efficient removal of phosphorus and nitrogen from aquatic environment using sepiolite-MgO nanocomposites: preparation, characterization, removal performance, and mechanism.

Excessive phosphorus will lead to eutrophication in aquatic environment; the efficient removal of phosphorus is crucial for wastewater engineering and surface water management. This study aimed to fabricate a nanorod-like sepiolite-supported MgO (S-MgO) nanocomposite with high specific surface area for efficient phosphate removal using a facile microwave-assisted method and calcining processes. The impact of solution pH, adsorbent dosage, contact time, initial phosphate concentrations, Ca addition, and N/P ratio on the phosphate removal was extensively examined by the batch experiments.

Modeling of arsenic migration and emission characteristics in coal-fired power plants.

After coal combustion, the minerals present in fly ash can adsorb arsenic (As) during flue gas cooling and reduce As emissions. However, a quantitative description of this adsorption behavior is lacking. Herein, the As adsorption characteristics of minerals (Al/Ca/Fe/K/Mg/Na/Si) were investigated, and a model was developed to predict As content in fly ash.

Enhance antimony adsorption from aquatic environment by microwave-assisted prepared FeO nanospherolites.

A novel hierarchically nanostructured magnetite (FeO) was manufactured using microwave-assisted reflux method without surfactants. The nanostructured FeO is formed via the co-precipitation of Fe(III) and Fe(II), followed by a nanocrystal aggregation-based mechanism. Moreover, the effects of solution pH, contact time, initial Sb concentration, coexisting anions, and recycle numbers on the adsorption of nanostructured FeO toward Sb were extensively examined in the batch adsorption tests.

Vitamin D3 Supplementation Attenuates Surgery-Induced Neuroinflammation and Cognitive Impairment by Regulating NLRP3 Inflammasome in Mice.

Neuroinflammation plays a dominant role in the progression of postoperative cognitive dysfunction (POCD). Vitamin D has been known to have important regulatory functions in inflammation and immune response. The NOD-like receptor protein 3 (NLRP3) is an essential inflammasome in the inflammatory response and could be activated by anesthesia and surgery.

Tripartite motif 72 inhibits apoptosis and mitochondrial dysfunction in neural stem cells induced by anesthetic sevoflurane by activating PI3K/AKT pathway.

Anesthetics exposure induces neurocognitive deficits during brain development and impairs self-renewal and differentiation of neural stem cells (NSCs). Tripartite motif 72 (TRIM72, also known as mitsugumin 53, MG53) is involved in tissue repair and plasma membrane damage repair. The neuroprotective effect of TRIM72 against sevoflurane-induced neurotoxicity of NSCs was investigated in this study.

Prediction of World Health Organization /International Society of Urological Pathology (WHO/ISUP) Pathological Grading of Clear Cell Renal Cell Carcinoma by Dual-Layer Spectral CT.

Rationale And Objectives: To evaluate whether the dual-layer spectral computed tomography urography (DL-CTU) images could predict WHO/ISUP pathological grading of clear cell renal cell carcinoma (ccRCC).

Materials And Methods: We retrospectively included patients (n = 50) with pathologically confirmed ccRCC who underwent preoperative DL-CTU (from October 2017 to February 2021). They were divided into low-grade (WHO/ISUP 1/2, n = 30) and high-grade groups (WHO/ISUP 3/4, n = 20).

Capturing effects of filamentous fungi Aspergillus flavus ZJ-1 on microalgae Chlorella vulgaris WZ-1 and the application of their co-integrated fungi-algae pellets for Cu(II) adsorption.

Using filamentous fungi to capture unicellular microalgae is an effective way for microalgae recovery in water treatment. Here, fungi Aspergillus flavus ZJ-1 and microalgae Chlorella vulgaris WZ-1 isolated from a copper tailings pond were used to study the capture effect of ZJ-1 on WZ-1. The highest capture efficiency (97.

Propofol postconditioning alleviates diabetic myocardial ischemia‑reperfusion injury the miR‑200c‑3p/AdipoR2/STAT3 signaling pathway.

Myocardial ischemia/reperfusion (MI/RI) syndrome is one of the leading causes of mortality and disability. Propofol postconditioning is known to improve myocardial ischemia/reperfusion injury (MI/RI). The present study aimed to explore the mechanism of propofol postconditioning in diabetic MI/RI.

Diagnostic significance of heart-type fatty acid-binding protein as a potential biomarker to predict the mortality rate of patients with sepsis: a systematic review and meta-analysis.

Background: Some studies have found that heart-type fatty acid-binding protein (H-FABP) is related to the prognosis of patients with sepsis. This study aimed to explore whether H-FABP could predict the 28-day mortality in patients with sepsis.

Methods: Seven databases were searched, and the studies were screened based on the inclusion and exclusion criteria to assess the quality.

Utilisation of virtual non-contrast images and virtual mono-energetic images acquired from dual-layer spectral CT for renal cell carcinoma: image quality and radiation dose.

Background: Renal cell carcinoma (RCC) is the most common renal malignant tumour. We evaluated the potential value and dose reduction of virtual non-contrast (VNC) images and virtual monoenergetic images (VMIs) from dual-layer spectral CT (DL-CT) in the diagnosis of RCC.

Results: Sixty-two patients with pathologically confirmed RCC who underwent contrast-enhanced DL-CT were retrospectively analysed.

Performance of an Artificial Intelligence-based Application for the Detection of Plaque-based Stenosis on Monoenergetic Coronary CT Angiography: Validation by Invasive Coronary Angiography.

Rationale And Objectives: To explore the value of an artificial intelligence (AI)-based application for identifying plaque-specific stenosis and obstructive coronary artery disease from monoenergetic spectral reconstructions on coronary computed tomography angiography (CTA).

Materials And Methods: This retrospective study enrolled 71 consecutive patients (52 men, 19 women; 63.3 ± 10.

Incorporating in vitro bioaccessibility into human health risk assessment of heavy metals and metalloid (As) in soil and pak choi (Brassica chinensis L.) from greenhouse vegetable production fields in a megacity in Northwest China.

The rapid development of greenhouse vegetable production (GVP) in densely populated areas may cause the heavy metal/metalloid accumulation in soil and pose a threat to human health. In this study, 180 pairs of topsoil and pak choi (Brassica chinensis L.) samples were collected from GVP fields in Xi'an city in Northwest China to analyze health risks of Cd, Cr, Pb, and As in soil and pak choi combining in vitro bioaccessibility investigation.

[Comparison of refracture risk between sandwich vertebrae and ordinary adjacent vertebrae].

Objective: To compare the refracture risk between sandwich vertebrae and ordinary adjacent vertebrae, and to explore the risk factors related to refracture.

Methods: Retrospective analysis was performed on the data of patients who received percutaneous vertebral augmentation (PVA) and formed sandwich vertebrae between April 2015 and October 2019. Of them, 115 patients were enrolled in the study.

Reduction of microwave ablation needle related metallic artifacts using virtual monoenergetic images from dual-layer detector spectral CT in a rabbit model with VX2 tumor.

The purpose of the study was to investigate the application of virtual monoenergetic images (VMIs) in reducing metal artifacts in rabbit VX2 liver cancer models treated with microwave ablation (MWA) therapy. A total of 31 VX2 liver cancer models that accepted CT-guided percutaneous microwave ablation were analyzed. Conventional images (CIs) with the most severe metallic artifacts and their corresponding energy levels from 40 to 200 keV with 10 keV increment of VMIs were reconstructed for further analysis.

Mechanism of selective gold adsorption on ion-imprinted chitosan resin modified by thiourea.

Thiourea-modified chitosan-imprinted resin (IM-TUCS) and a corresponding nonimprinted resin (NIM-TUCS) were synthesized and characterized using adsorption experiments. The adsorption results showed that adsorption reached equilibrium within 4 h. The adsorption data were better fitted using the Langmuir model (R>0.

Study of soil microorganisms modified wheat straw and biochar for reducing cadmium leaching potential and bioavailability.

The application of crops straw and biochar in trace metals remediation from the contaminated environment attracted more and more attention during the past decade. Although there has been some review work on the mechanism of trace metals stabilization by crops straw, the effects and mechanisms of interaction among soil indigenous-microbes and crops-straw for trace metal adsorption and stabilization is still unclear. In this study, the dynamic effects along with potential mechanisms of wheat-straw (WS), wheat-straw biochar (WBC) and biologically modified wheat-straw (BMWS) were conducted to investigate the adsorption, leaching behaviour, chemical fractions and bioavailability of cadmium (Cd).

Fracture-free probability and predictors of new symptomatic fractures in sandwich, ordinary-adjacent, and non-adjacent vertebrae: a vertebra-specific survival analysis.

Background: It is unclear whether the sandwich vertebra, is at higher risk of new symptomatic fractures (NSFs), and whether prophylactic augmentation might benefit patients with sandwich vertebrae.

Objective: To compare fracture-free probabilities of sandwich, ordinary-adjacent, and non-adjacent vertebrae, and identify predictors of NSFs.

Methods: Data were retrospectively analyzed for patients who had undergone vertebral augmentation resulting in sandwich vertebrae.

Experimental and DFT studies on the characteristics of PbO/PbCl adsorption by Si/Al- based sorbents in the simulated flue gas.

Mineral oxides are effective in-furnace sorbents used to control lead (Pb) emissions in flue gas at high temperatures. In this paper, the PbO/PbCl adsorption characteristics of sorbents were investigated via experimental and density functional theory (DFT) methods. The results show that Si/Al-based compounds can chemically adsorb Pb, and the adsorption is related to the Si-O and Al-O bonds in the sorbents.

Effects of ionic liquid [N] AOT on rice seedling growth cytomembrane damage and rhizobacteria resistance.

Ionic liquids (ILs) are solvents composed of ions, containing a large asymmetric cation with an anion. With increasing and widespread applications, the toxic effects of ILs have been considerable in recent years. This study explained the effects of the new functional ionic liquids [N] bis(2-ethylhexyl) sulfonyl succinate (AOT) on rice seedling and the growth of rhizobacteria.

Sevoflurane protects cardiomyocytes against hypoxia/reperfusion injury via LINC01133/miR-30a-5p axis.

Previous studies failed to elucidate the detailed mechanisms of anesthetic preconditioning as a protective approach against ischemic/reperfusion (I/R) injury in cells. The present study mainly centered on discovering the mechanisms of Sevoflurane (Sev) in preventing cardiomyocytes against I/R injury. Human cardiomyocyte AC16 cell line was used to simulate I/R injury based on a hypoxia/reperfusion (H/R) model.

Rhizosphere iron and manganese-oxidizing bacteria stimulate root iron plaque formation and regulate Cd uptake of rice plants (Oryza sativa L.).

Iron plaque is the amorphous and/or crystalline layer of Fe and Mn (hydr)oxides formed on the root surface of wetland plants. It could adsorb and co-precipitate metal(loid)s at the rhizosphere, thus modulating the uptake and accumulation of metal elements in plants. In this study, the Fe(II)/Mn(II)-oxidizing bacteria Burkholderia sp.