Mesenchymal stem cell-derived exosomes and skin photoaging: From basic research to practical application.

Background: Skin photoaging is a condition caused by long-term exposure to ultraviolet irradiation, resulting in a variety of changes in the skin, such as capillary dilation, increased or absent pigmentation, dryness, sagging, and wrinkles. Stem cells possess a remarkable antioxidant capacity and the ability to proliferate, differentiate, and migrate, and their main mode of action is through paracrine secretion, with exosomes being the primary form of secretion. Stem cell-derived exosomes contain a variety of growth factors and cytokines and may have great potential to promote skin repair and delay skin ageing.

Surgical treatment of pulsatile tinnitus related to the sigmoid sinus.

Objective: Tinnitus-a common clinical symptom-can be categorized into pulsatile tinnitus (PT) and non-PT. Among these, PT is usually associated with sigmoid sinus symptoms, such as sigmoid sinus wall defect or diverticulum, for which various surgical treatments are available. We have discussed the clinical efficacy of surgery for sigmoid sinus-associated PT via the transmastoid approach in this study.

Flexible endoscopy in the visualization of 3D-printed maxillary sinus and clinical application.

Background: During postoperative follow-up, the visible range of maxillary sinus (MS) is limited, even combining 0° and 70° rigid endoscopes together. Flexible endoscope has been used in larynx examinations for a long time, but rarely in nasal cavity and sinus. We aimed to evaluate the application values of rigid and flexible endoscopes for visualization of MS.

Metabolic Analysis of Potential Key Genes Associated with Systemic Lupus Erythematosus Using Liquid Chromatography-Mass Spectrometry.

The biological mechanism underlying the pathogenesis of systemic lupus erythematosus (SLE) remains unclear. In this study, we found 21 proteins upregulated and 38 proteins downregulated by SLE relative to normal protein metabolism in our samples using liquid chromatography-mass spectrometry. By PPI network analysis, we identified 9 key proteins of SLE, including AHSG, VWF, IGF1, ORM2, ORM1, SERPINA1, IGF2, IGFBP3, and LEP.

Stem cell-derived exosomes: A supernova in cosmetic dermatology.

Introduction: Stem cell-derived exosomes are cell-free vesicles secreted by stem cells. Exosomes play a pivotal role in cell-to cell communication due to the functional proteins and genetic information which they carry. In addition, studies on cell migration, tumor invasion, tissue regeneration, myocardial repair after injury, and fracture healing have been widely reported.

The prognostic value of before treatment neutrophil-to-lymphocyte ratio in nasopharyngeal carcinoma.

Objective: The aim of this analysis was to evaluate the prognostic significance of inflammatory biomarkers (NLR, dNLR, PLR and LMR) in NPC patients.

Methods: This was a retrospective analysis of 111 NPC patients from January 2013 and December 2016. Receiver-operating characteristic (ROC) curve was plotted to determine the cut-off values of these inflammatory biomarkers.

Presurgical platelet-lymphocyte ratio for prognosis in advanced hypopharyngeal squamous cell carcinoma in individuals undergoing radical resection.

Background: Patient prognosis in hypopharyngeal carcinoma remains difficult to predict, necessitating new, readily available biomarkers.

Objective: Platelet-lymphocyte ratio (PLR)'s effects on recurrence-free survival (RFS) and overall survival (OS) were evaluated in individuals undergoing radical resection for advanced hypopharyngeal squamous cell carcinoma (HSCC).

Methods: A total of 89 patients were retrospectively assessed.

Preoperative platelet-lymphocyte ratio predicts recurrence of laryngeal squamous cell carcinoma.

To evaluate the impact of preoperative platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), derived NLR (dNLR) and lymphocyte-monocyte ratio (LMR) on the prognosis of laryngeal squamous cell carcinoma. Overall survival and recurrence-free survival (RFS) were analyzed using Kaplan-Meier estimates. Multivariable Cox regression model was used to evaluate the independent prognostic significance of variables.

The prognostic value of preoperative derived neutrophil-to-lymphocyte ratio in patients undergoing total laryngectomy with laryngeal carcinoma.

Background: Emerging evidence indicate that inflammation plays a crucial role in carcinogenesis and tumor progression. Inflammatory response biomarkers are recognized as promising prognostic factors in laryngeal squamous cell carcinoma (LSCC).

Objective: To evaluate the prognostic significance of preoperative derived neutrophil-to-lymphocyte ratio (dNLR) in patients with total laryngectomy.

[Low-temperature-dependent Raman study on A1 (LO) mode of 6H-SiC].

Variable temperature method was lent for low temperature Raman study on bulk monocrystal 6H-SiC in the temperature range from 80 to 320 K. Some Raman folding modes of 6H-SiC were assigned in the spectrum. The peak position and line width of optical phonon A1 (LO) versus temperature mainly below RT was focused on by 3-phonon and 4-phonon models.

[A Raman study of ZnO powders with ZnO2 as precursor].

Raman spectra of ZnO powders prepared by firing ZnO2 precipitate were reported in detail for the first time. By comparing the spectra with that of the sample fabricated by another method and analyzing frequency difference between the focused-laser irradiated samples with different firing temperature in preparation, it was concluded that the -333 cm(-1) peak is ascribed to E2 (high)-E2 (low) and the -661 cm(-1) peak to its overtone. In addition, a new interpretation for the observed Raman peaks between 400 and 500 cm(-1) in ZnO2 powders was presented based on the IR data and ab initio calculation.