Bitter acids from Humulus lupulus L. alleviate D-galactose induced osteoblastic senescence and bone loss via regulating AKT/mTOR-mediated autophagy.

Bitter acids (BA) are main component of Humulus lupulus L. (hops). They are known for beer brewing and have various biological and pharmacological properties, especially the bone-protective effect confirmed by our previous in vivo study.

[Effects of astragaloside Ⅳ on inflammatory response and percentage of peripheral blood Th17 cells in mice with ulcerative colitis].

This study aimed to investigate the anti-inflammatory effect of astragaloside Ⅳ in mice with ulcerative colitis(UC) and its effect on the percentage of peripheral blood T helper(Th17) cells. Following the establishment of UC mouse model with 2% sodium dextran sulfate(DSS), mice in the positive control group and low-and high-dose astragaloside Ⅳ groups were treated with corresponding drugs by gavage. Disease activity index(DAI) was calculated, and serum interleukin-17(IL-17), tumor necrosis factor-α(TNF-α), and transforming growth factor-β(TGF-β) levels were assayed by ELISA.

[Study on the identification of Illicium vatum Hook. f. and illicium lanceolatum A. C. Smith by multi-ateps infrared macro-fingerprint method].

Illicium vatum Hook. f. and its counterfeit Illicium lanceolatum A.

[Analysis of Acanthopanax senticosus harms for different parts using Fourier transform infrared spectroscopy].

In the present paper, raw radix, stem and leaf and the total glycoside extract of them of Acanthopanax senticosus Harms were studied via the multi-steps IR macro-fingerprint method. The spectra of raw medicinal materials show that the spectra of radix and stem are similar and mainly show characteristic peaks of calcium oxalate and starch, whereas the characteristic peaks of calcium oxalate of leaf almost disappear and the shape of characteristic peak of starch also gets unconspicuous. The FT-IR spectra of total glycoside extract of radix, stem and leaf present characteristic peaks at 1602, 1514, 1452 cm(-1) (vibration of phenyl framework) and 1271 cm(-1) (==C--O), respectively, therefore, the authors speculated that their mutual component is the compound of phenolic glycoside.