Publications by authors named "Sheng-Nan Yu"

Purpose: To explore the predictive potential of intratumoral and multiregion peritumoral radiomics features extracted from multiparametric MRI for predicting pathological differentiation in hepatocellular carcinoma (HCC) patients.

Methods: A total of 265 patients with 277 HCCs (training cohort n = 193, validation cohort n = 84) who underwent preoperative MRI were retrospectively analyzed. The risk factors identified through stepwise regression analysis were utilized to construct a clinical model.

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Objective: Arsenic (As) and fluoride (F) are two of the most common elements contaminating groundwater resources. A growing number of studies have found that As and F can cause neurotoxicity in infants and children, leading to cognitive, learning, and memory impairments. However, early biomarkers of learning and memory impairment induced by As and/or F remain unclear.

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Article Synopsis
  • Vinyl chloride (VC) is an environmental pollutant that worsens liver fat accumulation (hepatic steatosis) when combined with a high-fat diet, particularly in recent dietary shifts among Chinese populations.
  • Research shows that exposure to VC exacerbates oxidative stress and endoplasmic reticulum stress in the liver, leading to increased levels of proteins associated with fat production.
  • Antioxidants and inhibitors targeting stress responses can help reduce liver fat buildup caused by VC and its metabolite, indicating potential pathways for managing liver disease risks linked to dietary changes.
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Hypertension is a common chronic disease in middle-aged and elderly people and is an important risk factor for many cardiovascular diseases. Its pathogenesis remains unclear. Epidemiological studies have found that the loss of telomere length in peripheral blood cells can increase the risk of coronary heart disease, myocardial infarction, and other diseases.

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Background: Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system characterized by severe white matter demyelination. Because of its complex pathogenesis, there is no definite cure for MS. Experimental autoimmune encephalomyelitis (EAE) is an ideal animal model for the study of MS.

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The cumulative adsorption of external phosphorus (P) by water purification sludge after ignition under different addition methods (mix and cover) was investigated along with the adsorption isotherm and the release of internal P after external P adsorption. The cumulative adsorption of external P was 11.496 mg (mix) and 11.

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The adsorption of external phosphorus (P) and the distribution of dissolved inorganic P (DIP) in the sediment interstitial water and sedimentary P forms were researched under the ignited water purification sludge (IWPS) addition (mixing and capping). The results showed that the adsorption ability of the IWPS increased obviously, compared with the water purification sludge (WPS). It indicated that the increased by 43.

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This work aimed to clarify the influence of multiple disturbance factors on the migration and transformation of endogenous phosphorus. In this experiment, the sediment of Meiliang Bay in Taihu Lake was studied as the major research object. With the help of Rhizon sampling technique, Unisense microelectrode system and so on, this experiment studied the change regularities of dissolved oxygen between sediment and water interface, different forms of phosphorus and iron ions under disturbance.

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Background: During the past years, the number of liver transplantation has increased greatly, but the number of available organs has not increased. In view of the critical shortage of organs, the indications for living-related liver transplantation (LRLT) have broadened since experience with the procedure has been achieved. This study was undertaken to assess the value of multi-slice spiral CT (MSCT) angiography in evaluating the hepatic arterial and veinous anatomy of potential donors for LRLT.

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