Formulated chitosan-sodium tripolyphosphate nanoparticles for co-encapsulation of ellagic acid and anti-inflammatory peptide: characterization, stability and anti-inflammatory activity.

Background: Chitosan (CS) and tripolyphosphate (TPP) can be combined in the development of a material with synergistic properties and promising potential for the conservation of food products. In this study, ellagic acid (EA) and anti-inflammatory peptide (FPL)-loaded CS nanoparticles (FPL/EA NPs) were prepared using the ionic gelation method and optimal preparation conditions were obtained through a single factor design.

Results: The synthesized nanoparticles (NPs) were characterized using a scanning electron microscope (SEM), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and differential scanning calorimetry (DSC).

Preparation, identification, and molecular docking of novel elastase inhibitory peptide from walnut ( L.) meal.

This study aimed to isolate bioactive peptides with elastase inhibitory activity from walnut meal via ultrasonic enzymatic hydrolysis. The optimal hydrolysis conditions of walnut meal protein hydrolysates (WMPHs) were obtained by response surface methodology (RSM), while a molecular weight of<3 kDa fraction was analyzed by LC-MS/MS, and 556 peptides were identified. PyRx virtual screening and Autodock Vina molecular docking revealed that the pentapeptide Phe-Phe-Val-Pro-Phe (FFVPF) could interact with elastase primarily through hydrophobic interactions, hydrogen bonds, and π-sulfur bonds, with a binding energy of -5.

Triphasic dynamic enhanced computed tomography for differentiating cholesterol and adenomatous gallbladder polyps.

Background: Triphasic dynamic enhanced computed tomography (CT) scans were acquired to identify cholesterol and adenomatous gallbladder (GB) polyps that were inaccurately diagnosed before surgery.

Purpose: To evaluate the CT findings of 1.0- to 2.

Dual-energy CT to differentiate gallbladder polyps: cholesterol versus adenomatous.

Background: Dual-energy computed tomography (DE-CT) scans were acquired to identify cholesterol and adenomatous gallbladder (GB) polyps, which have not been well evaluated before surgery.

Purpose: To evaluate the DE-CT findings of GB polyps 1.0-2.

Novel metal nanoparticle-enhanced fluorescence for determination of trace amounts of fluoroquinolone in aqueous solutions.

Metal-enhanced fluorescence of fluoroquinolones (FQs) was first observed in aqueous solutions. In addition, a new type of silver nanoparticles (AgNP) was synthesized with simple and easy synthetic processes and environmentally friendly compounds. The effects of different concentrations of AgNPs on the fluorescence behaviours of ciprofloxacin (CIP), enrofloxacin (ENR) and lomefloxacin (LMF) in aqueous solutions were investigated, respectively.