Publications by authors named "Sheng-Chih Chu"
To analyze the factors associated with in-hospital mortality of children with acute fulminant myocarditis on venoarterial extracorporeal membrane oxygenation (VA-ECMO). This was a retrospective cohort study using chart reviews of patients diagnosed with acute fulminant myocarditis at the pediatric intensive care unit of two tertiary medical centers between January 1, 2005 and December 31, 2017. The inclusion criteria for this study were: (1) age from 1 month to 18 years; (2) diagnosed with acute myocarditis; (3) cardiogenic shock and need vasoactive-inotropic score ≥20 within 48 h after the use of vasoactive-inotropic agents; and (4) the need for ECMO placement.
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- The study investigates the link between hemodynamic measurements, serum lactate levels, and 28-day mortality in children experiencing persistent catecholamine-resistant shock.
- Out of 26 children monitored, the mortality rate was 53.8%, with systemic vascular resistant index (SVRI) and vasoactive-inotropic score (VIS) identified as independent predictors of mortality.
- SVRI showed a strong correlation with serum lactate and was a better indicator of mortality risk compared to lactate levels, with an SVRI below 1284 dyn·s·cm·m associated with higher mortality, highlighting its potential as an early warning sign in this critically ill population.