[Distribution Characteristics of Disinfection By-Products and the Effects of Booster Chlorination in Long-Distance Water Supply Systems].

It is difficult for waterworks that add chlorine into finished water once to maintain sufficient residual chlorine at unfavorable points of the pipe network that supply water for large areas of coverage. Therefore, booster chlorination was employed for a long-distance water distribution system. The study was performed in H City with a water supply system serving about 400 km of downtown and rural areas.

Thermoelectric Properties of Bismuth Telluride Thin Films Electrodeposited from a Nonaqueous Solution.

We report the thermoelectric properties of BiTe thin films electrodeposited from the weakly coordinating solvent dichloromethane (CHCl). It was found that the oxidation of porous films is significant, causing the degradation of its thermoelectric properties. We show that the morphology of the film can be improved drastically by applying a short initial nucleation pulse, which generates a large number of nuclei, and then growing the nuclei by pulsed electrodeposition at a much lower overpotential.

Solar-Driven Carbon Nanoreactor Coupling Gold and Platinum Nanocatalysts for Alcohol Oxidations.

This research reports gold (Au) and platinum (Pt) nanocatalysts spatially confined in a porous carbon nanosphere as a new solar-driven carbon nanoreactor (CNR). The CNRs have confined size (≈100 nm), high specific surface area, and high thermal and electrical conductivity. The black color of CNR can improve the energy harvest efficiency of the solar irradiation to thermal energy within each nanoreactor.

Epidemiological features and viral shedding in children with SARS-CoV-2 infection.

A pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection broke out all over the world; however, epidemiological data and viral shedding in pediatric patients are limited. We conducted a retrospective, multicenter study, and followed-up with all children from the families with SARS-CoV-2 infected members in Zhejiang Province, China. All infections were confirmed by testing the SARS-CoV-2 RNA with real-time reverse transcription PCR method, and epidemiological data between children and adults in the same families were compared.

In-situ formation of carboxylate species on TiO nanosheets for enhanced visible-light photocatalytic performance.

It still remains challenge for expanding the photo-response range of TiO with dominant {0 0 1} facets due to the hardly achieving modification of the electronic structure without destroying the formation of TiO high energy facets. Herein, we report the construction of carboxylate species modified TiO nanosheets with dominant {0 0 1} facets by employing ethanol as a carbon source through a low-temperature (300 °C) carbonization method. The as-obtained samples were investigated in detail by using various characterization techniques.

Identification of causing an unexplained disease cluster in Matthews Ridge, Guyana.

Here, we report the identification of causing an unexplained disease cluster in Matthews Ridge, Guyana. In March 2019, 14 employees of Chongqing Bosai Mining Company, China, working in a manganese mining of Guyana, had unexplained fever, and two of them died. We obtained lung and brain tissues as well as the blood samples from the two deceased cases (patient No.

Effect of high-volume hemofiltration on children with sepsis.

Background: Sepsis has always been a challenge in pediatric intensive care unit (PICU) with poor prognosis. In order to evaluate the effect between routine continuous renal replacement therapy (CRRT) and high-volume hemofiltration (HVHF) in children with sepsis, we performed out this prospective, randomized, controlled, open-label trial.

Methods: Forty-seven children with sepsis were enrolled from January 2015 to December 2016.

Embedded Metal Oxide Plasmonics Using Local Plasma Oxidation of AZO for Planar Metasurfaces.

New methods for achieving high-quality conducting oxide metasurfaces are of great importance for a range of emerging applications from infrared thermal control coatings to epsilon-near-zero nonlinear optics. This work demonstrates the viability of plasma patterning as a technique to selectively and locally modulate the carrier density in planar Al-doped ZnO (AZO) metasurfaces without any associated topographical surface profile. This technique stands in strong contrast to conventional physical patterning which results in nonplanar textured surfaces.

Cooperative transport mechanism of human monocarboxylate transporter 2.

Proton-linked monocarboxylate transporters (MCTs) must transport monocarboxylate efficiently to facilitate monocarboxylate efflux in glycolytically active cells, and transport monocarboxylate slowly or even shut down to maintain a physiological monocarboxylate concentration in glycolytically inactive cells. To discover how MCTs solve this fundamental aspect of intracellular monocarboxylate homeostasis in the context of multicellular organisms, we analyzed pyruvate transport activity of human monocarboxylate transporter 2 (MCT2). Here we show that MCT2 transport activity exhibits steep dependence on substrate concentration.

Value of Gd-EOB-DTPA-Enhanced MRI and Diffusion-Weighted Imaging in Detecting Residual Hepatocellular Carcinoma After Drug-Eluting Bead Transarterial Chemoembolization.

Rationale And Objectives: To investigate the value of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) in diagnosing residual hepatocellular carcinoma (HCC) after drug-eluting bead transarterial chemoembolization (DEB-TACE).

Materials And Methods: Sixty-two patients (50 men, 12 women; mean age, 56.8 ± 1.

[Diagnosis and treatment recommendation for pediatric COVID-19 (the second edition)].

The coronavirus disease 2019 (COVID-19) has caused a global pandemic. All people including children are generally susceptible to COVID-19, but the condition is relatively mild for children. The diagnosis of COVID-19 is largely based on the epidemiological evidence and clinical manifestations, and confirmed by positive detection of virus nucleic acid in respiratory samples.

Research and development of drug delivery systems based on drug transporter and nano-formulation.

In recent years, the continuous occurrence of multi-drug resistance in the clinic has made people pay more attention to the transporter. Changes in the expression and activity of transporters can cause corresponding changes in drug pharmacokinetics and pharmacodynamics. The drug-drug interactions (DDI) caused by transporters can seriously affect drug effectiveness and toxicity.

Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19.

Background: Anti-SARS-CoV-2 virus antibody levels in convalescent plasma (CP), which may be useful in severe Anti-SARS-CoV-2 virus infections, have been rarely reported.

Results: A total of eight donors were considered for enrollment; two of them were excluded because of ineligible routine check. Of the six remaining participants, five samples were tested weakly positive by the IgM ELISA.

Label-free detection of cancer related gene based on target recycling and palindrome-mediated strand displacement amplification.

STAT3 plays an important role in regulating gene expression and is closely related with cancer. Thus, the sensitive and specific detection of the STAT3 biomarker is of great importance for disease diagnosis and therapeutics. In this study, by combining the target recycling amplification (TRA) with strand displacement amplification (SDA), we have developed a label-free and highly sensitive method for the dual-amplified detection of STAT3.

Electric Dipole Descriptor for Machine Learning Prediction of Catalyst Surface-Molecular Adsorbate Interactions.

The challenge of evaluating catalyst surface-molecular adsorbate interactions holds the key for rational design of catalysts. Finding an experimentally measurable and theoretically computable descriptor for evaluating surface-adsorbate interactions is a significant step toward achieving this goal. Here we show that the electric dipole moment can serve as a convenient yet accurate descriptor for establishing structure-property relationships for molecular adsorbates on metal catalyst surfaces.

MG-132 attenuates cardiac deterioration of viral myocarditis via AMPK pathway.

Background: Coxsackievirus B3 (CVB3) is the primary cause of infectious myocarditis. Aggressive immunological activation and apoptosis of myocytes contributes to progressive dysfunction of cardiac contraction and poor prognosis. MG-132, a proteasome inhibitor, regulates mitochondrial-mediated intrinsic myocardial apoptosis and downregulates NF-κB-mediated inflammation.

Junctional and somatic hypermutation-induced CXC motif is critical for the recognition of a highly conserved epitope on HCV E2 by a human broadly neutralizing antibody.

Induction of broadly neutralizing monoclonal antibodies (bNAbs) that bind to the viral envelope glycoproteins is a major goal of hepatitis C virus (HCV) vaccine research. The study of bNAbs arising in natural infection is essential in this endeavor. We generated a human antibody, 8D6, recognizing the E2 protein of HCV isolated from a chronic hepatitis C patient.

[Emergency plan for inter-hospital transfer of newborns with SARS-CoV-2 infection].

Since December 2019, the outbreak of coronavirus disease (COVID-19) has become the most serious public health issue. As the special population with immature immune function, newborns with COVID-19 have been reported. Newborns with suspected or confirmed COVID-19 should be transferred to designated hospitals for isolation treatment.

Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus.

Since December 2019, an epidemic caused by novel coronavirus (2019-nCoV) infection has occurred unexpectedly in China. As of 8 pm, 31 January 2020, more than 20 pediatric cases have been reported in China. Of these cases, ten patients were identified in Zhejiang Province, with an age of onset ranging from 112 days to 17 years.

Epigenetic Mechanisms Underlying Organic Solute Transporter Repression in Colorectal Cancer.

Colorectal cancer (CRC) is known to be the third most common cancer disease and the fourth-leading cause of cancer-related deaths worldwide. Bile acid, especially deoxycholic acid and lithocholic acid, were revealed to play an important role during carcinogenesis of CRC. In this study, we found organic solute transporter (OST), an important subunit of a bile acid export transporter OST-OST, was noticeably downregulated in CRC.

Oral health knowledge, beliefs and practices among community-dwelling older adults in Shanghai, China: A cross-sectional analysis.

Objective: To assess oral health knowledge, beliefs and practices among community-dwelling older adults in Shanghai, China.

Background: China is ageing faster than other developing countries. Four National Oral Health Surveys have been carried out in China between 1983 and 2015, focused on clinical oral examinations.

Internal-Field-Enhanced Charge Separation in a Single-Domain Ferroelectric PbTiO Photocatalyst.

Ferroelectric materials with spontaneous polarization-induced internal electric fields have drawn increasing attention in solar fuel production due to the intrinsic polarized structure. However, the origination of charge separation in these materials at the nano/microlevel is ambiguous owing to the complexity of the multielectric fields. Besides, the observed charge separation ability is far from theoretical expectation.