Publications by authors named "Sheng Xi Han"
Background And Aims: The current methods for treatment of giant gastric bezoars mainly include chemical dissolution, endoscopic fragmentation, and surgical removal, which often have limited curative effects or generate multiple adverse events. Therefore, there is an urgent need to find new methods to overcome such a dilemma. The aim of this study was to evaluate the safety, efficacy, and feasibility of a novel guidewire-based tangential sawing fragmentation (GTSF) technique to treat giant gastric bezoars.
View Article and Find Full Text PDFBackground And Aims: The efficacy of PPI-amoxicillin dual therapy (high-dose dual therapy) in the eradication of Helicobacter pylori is controversial. We aimed to investigate whether PPI-amoxicillin dual therapy is effective.
Methods: We searched several publication databases for randomized controlled trials (RCTs) that compared PPI-amoxicillin dual therapy with controls up to March 2019.
Article Synopsis
- This study compared the effectiveness and side effects of high-dose dual therapy (HDDT) and bismuth quadruple therapy (BQT) for treating Helicobacter pylori infections through a systematic review and meta-analysis of existing clinical trials up to March 2018.!* -
- Four randomized clinical trials involving 829 patients were analyzed, showing similar eradication rates for both treatments around 85-87%, but BQT had significantly more side effects (40.4% compared to 14.4% for HDDT).!* -
- The findings suggest that while both therapies are effective in eradicating H. pylori, HDDT is associated with fewer side effects, making it a potentially preferable option for
Objective: Although some studies have reported >90% success with high-dose dual proton pump inhibitor (PPI)-amoxicillin dual therapy for Helicobacter pylori (H. pylori) eradication, the efficacy of this therapy remains controversial. We aimed to re-evaluate the efficacy and safety of high-dose dual therapy on H.
View Article and Find Full Text PDF