Publications by authors named "Sheng Shu"

In this study, the effects of goji berry (Lycium barbarum L.) grafting on tomato growth, photosynthesis, antioxidant metabolism and osmoregulatory substances under high-temperature stress were studied with black goji berry and red goji berry as grafting rootstocks and 'Sufen 14' tomato as scions. It was found that under room temperature conditions, the growth of goji berry grafted tomato plants was inhibited compared to self-rooted tomato plants, and goji berry rootstock grafting could alleviate the adverse effects of high-temperature stress on plant height, stem diameter, and root activity.

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In order to study the effects of different types of acid pretreatment of pigskin on the gel characteristics and traceability aspects of the extracted gelatin, the molecular weight distribution and gelling properties of pigskin gelatin were studied using SDS-PAGE, texture analyzer, and rheometer. The characteristic peptides digested from pigskin gelatin were studied by HPLC-MS/MS technique. The findings revealed that gelatin extracted from pigskin pretreated with acetic acid showed the most typical bands.

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Black wolfberry ( Murr.) is an important plant for ecological preservation. In addition, its fruits are rich in anthocyanins and have important edible and medicinal value.

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Controlling the suitable light, temperature, and water is essential for plant photosynthesis. While greenhouses/warm-houses are effective in cold or dry climates by creating warm, humid environments, a cool-house that provides a cool local environment with minimal energy and water consumption is highly desirable but has yet to be realized in hot, water-scarce regions. Here, using a synergistic genetic algorithm and machine learning, we propose and demonstrate a coolhouse film that regulates temperature and water for photosynthesis without requiring additional energy or water.

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Objective: To investigate the clinical efficacy of thoracoscopic minimally invasive surgery with nickel-titanium shape memory alloy wrap bone plate versus rib periosteal internal fixation in patients with multiple rib fractures (MRF) and flail chest.

Methods: A retrospective analysis was performed on 100 patients with MRF and flail chest treated with thoracoscopic minimally invasive surgery and internal fixation with rib fracture preservation between January 2019 and December 2022, including 54 males and 46 females, aged from 20 to 65 years old, with an average age of (38.0±18.

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Cotton is an important source of natural fibers. The AP2/ethylene response factor (ERF) family is one of the largest plant-specific transcription factors (TFs) groups, playing key roles in plant growth and development. However, the role of ERF TFs in cotton's growth and development remains unclear.

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Cotton (Gossypium hirsutum L.) is one of the world's most important commercial crops. However, the dynamics of metabolite abundance and potential regulatory networks throughout its life cycle remain poorly understood.

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Article Synopsis
  • - The study reviews advancements in research on RET rearrangements in solid tumors, specifically focusing on therapeutic strategies and outcomes in advanced non-small cell lung cancer (NSCLC) within China.
  • - It analyzes the incidence of RET rearrangements, treatment approaches, and evaluates the effectiveness of targeted RET inhibitors, particularly assessing real-world patient outcomes.
  • - A retrospective analysis of 64 patients shows that the KIF5B-RET fusion is the most common, with Pralsetinib achieving a median progression-free survival of 16.03 months, significantly better than chemotherapy.
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Background: The malignant tumor that has the highest global morbidity and death rate is lung cancer, which primarily affects the elderly. The therapy landscape for non-small cell lung cancer (NSCLC) has transformed with the introduction of immune checkpoint inhibitors (ICIs). The purpose of this study was to compare the safety and efficacy of immune monotherapy and immunotheray combined with chemotherapy in patients with advanced NSCLC aged 75 years and above.

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Lung cancer is the top cause of cancer deaths globally. Advances in immune checkpoint inhibitors (ICIs) have transformed cancer treatment, but their use in lung cancer has led to more side effects. This study examined if past pulmonary tuberculosis (TB) affects ICIs' effectiveness and safety in lung cancer treatment.

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Cotton fiber (Gossypium hirsutum) serves as an ideal model for investigating the molecular mechanisms of plant cell elongation at the single-cell level. Brassinosteroids (BRs) play a crucial role in regulating plant growth and development. However, the mechanism by which BR influences cotton fiber elongation remains incompletely understood.

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Article Synopsis
  • * It is rich in various nutrients like soluble sugars, vitamins, and minerals, which contribute to benefits such as improving digestion, reducing cholesterol, and promoting overall health.
  • * The article discusses daylily’s drying process, its biological activities, and the need for further research on its molecular mechanisms to enhance understanding and industry applications.
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Article Synopsis
  • The majority (75%) of non-small cell lung cancer (NSCLC) patients are 65 years or older, and immune checkpoint inhibitors (ICIs) have changed how NSCLC is treated.
  • Studies show that ICIs effectively benefit patients aged 65-75 and can be combined with chemotherapy or radiotherapy, but their effectiveness decreases for those over 75.
  • Older patients (≥75 years) may experience higher-grade immune-related adverse events (irAEs) with combination treatments, highlighting the need for more research on immunotherapy tailored for elderly patients with NSCLC.
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Triboelectric nanogenerators (TENGs) have emerged as a promising approach for generating electricity and providing electrical stimuli in medical electronic devices. Despite their potential benefits, the clinical implementation of TENGs faces challenges such as skin compliance and a lack of comprehensive assessment regarding their biosafety and efficacy. Therefore, further research is imperative to overcome these limitations and unlock the full potential of TENGs in various biomedical applications.

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  • Muscle strength (MS) is crucial for diagnosing and evaluating rehabilitation, and existing wearable technologies have limitations in accuracy and analysis methods.
  • This study introduces a wearable device that uses myoelectric and strain sensors to accurately measure muscle signals during activities, employing a new deep learning model called Tcnformer for precise MS grading.
  • By utilizing deep clustering, the research achieves a detailed 25-level classification of MS, demonstrating its potential to improve recovery assessment in clinical settings, as shown by a patient's postoperative improvement from level 3.2 to 3.6.
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Levels of lipopolysaccharide (LPS), an essential glycolipid on the surface of most gram-negative bacteria, are tightly controlled-making LPS synthesis a promising target for developing new antibiotics. adaptor protein LapB (YciM) plays an important role in regulating LPS synthesis by promoting degradation of LpxC, a deacetylase that catalyzes the first committed step in LPS synthesis. Under conditions where LPS is abundant, LapB recruits LpxC to the AAA+ protease FtsH for degradation.

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Article Synopsis
  • The study aimed to identify key mental health challenges faced by hospital administrators working from home during the COVID-19 normalization phase.
  • Conducted via surveys with 33 administrators, the research utilized the DEMATEL method to establish relationships between various mental health factors affecting their work.
  • Findings highlight that major issues include lack of coordination, time management difficulties, and work-life imbalances, with recommendations to improve conditions around improper guidelines and job insecurity to support their mental well-being.
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Polarization-sensitive photodetectors have attracted considerable attention owing to their potential application prospects in navigation, optical switching, and communication. However, it remains challenging to develop a facile and effective strategy to simultaneously meet the demands of low power consumption, high performance, and excellent polarization sensitivity. Herein, a series of low-symmetry two-dimensional (2D) ReSe Schottky photodetectors with geometry-asymmetric contacts are constructed.

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Innovative functional electrical stimulation has demonstrated effectiveness in enhancing daily walking and rehabilitating stroke patients with foot drop. However, its lack of precision in stimulating timing, individual adaptivity, and bilateral symmetry, resulted in diminished clinical efficacy. Therefore, a closed-loop wearable device network of intrinsically controlled functional electrical stimulation (CI-FES) system is proposed, which utilizes the personal surface myoelectricity, derived from the intrinsic neuro signal, as the switch to activate/deactivate the stimulation on the affected side.

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The color of purple carrot taproots mainly depends on the anthocyanins sequestered in the vacuoles. Glutathione S-transferases (GSTs) are key enzymes involved in anthocyanin transport. However, the precise mechanism of anthocyanin transport from the cytosolic surface of the endoplasmic reticulum (ER) to the vacuoles in carrots remains unclear.

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Routing and security are the two main prerequisites for ensuring the correct operation of wireless networks. The importance of these cases doubles in wide networks such as IoT. This paper presents an algorithm to improve Secure Routing in IoT called SRAIOT.

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As one of the key enzymes in the biosynthesis of polyamines, S-adenosylmethionine decarboxylase (SAMDC) plays an important role in plant stress resistance. In this study, four genes were identified in cucumber ( L.) and divided into three groups (I, II, and III) by phylogenetic analysis.

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an outer membrane (OM), a peptidoglycan cell wall, and an inner membrane (IM). The OM and IM have different components of proteins and lipids. Separating the IM and OM is a basic biochemical procedure to further study lipids and membrane proteins in different locations.

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Article Synopsis
  • - The receptor tyrosine kinase KIT, along with its ligand stem cell factor (SCF), is essential for developing various cell types, and mutations in KIT are linked to several human cancers, like leukemia and gastrointestinal tumors.
  • - Cryo-electron microscopy studies reveal structural differences between normal and mutated forms of KIT, particularly in the extracellular domain, suggesting that the D5 region may be a critical target for new cancer therapies.
  • - Oncogenic KIT mutants show different conformations, with one mutant reverting to a wild-type structure upon SCF binding, highlighting the potential for drug development aimed at restoring or targeting these conformational changes.
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Inspired by natural biological systems, soft robots have recently been developed, showing tremendous potential in real-world applications because of their intrinsic softness and deformability. The confluence of electronic skins and machine learning is extensively studied to create effective biomimetic robotic systems. Based on a differential piezoelectric matrix, this study presents a shape-sensing electronic skin (SSES) that can recognize surface conformations with minimal interference from pressing, stretching, or other surrounding stimuli.

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