Research on polarization effect suppression method of weak starlight simulation device.

Under the influence of the polarization effect, the background stray light of the weak starlight simulator and the polarization state of the simulated target star point are doped with each other, so it is difficult to achieve accurate suppression of polarized stray light. In this paper, the mechanism of background stray light induced by the optical engine in a weak starlight simulation device is analyzed, and the principle of mutual doping between stray light and simulated target starlight polarization state is studied. The correlation model of polarization parameters, point source transmittal, and simulated target magnitude was established, and the optimization process of polarization effect was constructed to achieve accurate suppression of polarized stray light in the star map background.

Optimization of polarization balance in beam splitter films for weak star simulator.

In the weak star simulator, the background stray light of the self-excited star image and the simulated target star light are mixed with each other, which is difficult to separate and reduces the simulation accuracy of the star position. Therefore, based on the polarized light tracing method, this paper explores the induction mechanism of the polarization effect of the weak star simulator on the background stray light field of the star map, and proposes a polarization balance optimization method for the beam splitter film. At the same time, the mapping model of star position simulation accuracy, polarization parameters of beam splitter and polarization stray light suppression degree is established.

Anisotropic van der Waals Tellurene-Based Multifunctional, Polarization-Sensitive, In-Line Optical Device.

Polarization plays a paramount role in scaling the optical network capacity. Anisotropic two-dimensional (2D) materials offer opportunities to exploit optical polarization-sensitive responses in various photonic and optoelectronic applications. However, the exploration of optical anisotropy in fiber in-line devices, critical for ultrafast pulse generation and modulation, remains limited.

Gradient-induced long-range optical pulling force based on photonic band gap.

Optical pulling provides a new degree of freedom in optical manipulation. It is generally believed that long-range optical pulling forces cannot be generated by the gradient of the incident field. Here, we theoretically propose and numerically demonstrate the realization of a long-range optical pulling force stemming from a self-induced gradient field in the manipulated object.

An Adaptive Region-Based Transformer for Nonrigid Medical Image Registration With a Self-Constructing Latent Graph.

Nonrigid registration of medical images is formulated usually as an optimization problem with the aim of seeking out the deformation field between a referential-moving image pair. During the past several years, advances have been achieved in the convolutional neural network (CNN)-based registration of images, whose performance was superior to most conventional methods. More lately, the long-range spatial correlations in images have been learned by incorporating an attention-based model into the transformer network.

Constructing Type-II and S-Scheme Heterojunctions of CuO@Cu(SO)(OH)·HO Polyhedra by In Situ Etching CuO with Different Exposed Facets for Enhanced Photocatalytic Sterilization and Degradation Performance.

The construction of type-II or S-scheme heterojunctions can effectively accelerate the directional migration of charge carriers and inhibit the recombination of electron-hole pairs to improve the catalytic performance of the composite catalyst; therefore, the construction and formation mechanism of a heterojunction are worth further investigation. Herein, CuO@Cu(SO)(OH)·HO core-shell polyhedral heterojunctions were fabricated via in situ etching CuO with octahedral, cuboctahedral, and cubic shapes by sodium thiosulfate (NaSO). CuO@Cu(SO)(OH)·HO polyhedral heterojunctions demonstrated obviously enhanced sterilization and degradation performance than the corresponding single CuO polyhedra and Cu(SO)(OH)·HO.

Pillar[5]arene-Based AIE Supramolecular Polymer Networks Exhibiting Various Fluorescence to Achieve Visible Surveillance.

Supramolecular polymer networks (SPNs) based on pillar[n]arene are widely studied and it is known that evolution from linear polymers to SPNs occurs as a progressive process, which is of importance to monitor the detailed morphology throughout the process. Yet, the current reports related to that distinction by employing fluorescence approach have realized confined success, it still remains a challenge to distinguish the various states visually. Herein, a fluorescent group of the pyrene benzohydrazonate-based (PBHZ-based) derivative is introduced into the pillar[5]arene based SPNs gained from host-guest recognition, enabling the visual monitoring during the formation of SPNs.

Characterization of SHCBP1 to prognosis and immunological landscape in pan-cancer: novel insights to biomarker and therapeutic targets.

Background: Previous studies have revealed the significant roles of SHC SH2 domain-binding protein 1 (SHCBP1) in occurrence and progression of cancers, but there is no pan-cancer analysis of SHCBP1.

Methods: In this study, we explored the potential carcinogenic role of SHCBP1 across 33 tumors from the TCGA and GTEx databases. We investigated SHCBP1 expression, prognosis, genetic alterations, tumor mutational burden (TMB) score, microsatellite instability (MSI) and tumor microenvironment from TIMER2, GEPIA2, UALCAN and cBioPortal databases.

Dissection of pyroptosis-related prognostic signature and CASP6-mediated regulation in pancreatic adenocarcinoma: new sights to clinical decision-making.

Recent studies have indicated that pyroptosis may participate in the regulation of tumorigenesis and immune microenvironment. However, the role of pyroptosis-related genes (PRGs) in pancreatic adenocarcinoma (PAAD) remains unclear. Through multiple bioinformatics analysis, we constructed a prognostic gene model and competing endogenous RNA network.

Highly localized, efficient, and rapid photothermal therapy using gold nanobipyramids for liver cancer cells triggered by femtosecond laser.

In this study, the photothermal effect and up-conversion florescence imaging effect of gold nanobipyramids in liver cancer cells are investigated theoretically and experimentally to explore the photothermal ablation tumor therapy with higher photothermal conversion efficiency, shorter laser action time, smaller action range and lower laser power. The small-size gold nanobipyramids with good biocompatibility and infrared absorption peak located in the first biological window are synthesized. Femtosecond laser is focused on the nanobipyramids clusters in cells and the cells die after being irradiated for 20 s at a power as low as 3 mW.

Deciphering a mitochondria-related signature to supervise prognosis and immunotherapy in hepatocellular carcinoma.

Background: Hepatocellular carcinoma (HCC) is a major public health problem in humans. The imbalance of mitochondrial function has been discovered to be closely related to the development of cancer recently. However, the role of mitochondrial-related genes in HCC remains unclear.

Upregulated UBE4B expression correlates with poor prognosis and tumor immune infiltration in hepatocellular carcinoma.

Background: Hepatocellular carcinoma (HCC) is a major human health concern. Increasing evidence has demonstrated that ubiquitin ligase E4B (UBE4B) may be involved in the occurrence and development of various human cancers and may affect prognosis. However, the specific role and mechanism of UBE4B in HCC is unclear.

"Enzyme-Like" Spatially Fixed Polyhydroxyl Microenvironment-Activated Hydrochromic Molecular Switching for Naked Eye Detection of ppm Level Humidity.

The detection and monitoring of ultralow humidity (<100 ppm) are critical in many important industries, such as high-tech manufacturing, scientific research, and aerospace. However, the development of ppm level humidity sensors with portability, low cost, and ease of regeneration remains a significant challenge. Herein, an innovative "enzyme-like" construction strategy is proposed to address this problem by employing suitable molecular-level humidity-sensitive units and chemically constructing a multilevel spatial synergistic sensitization microenvironment around it.

Turning a polystyrene microsphere into a multimode light source by laser irradiation.

Polystyrene (PS) is generally considered as a passive optical material that is transparent to light with wavelengths longer than 300 nm. In practice, PS micro- and nanospheres with uniform sizes are usually used to build photonic crystals based on self-assembly mechanism. Here, we demonstrate experimentally that PS microspheres supporting whispery gallery modes can be transformed into multimode light sources by laser irradiation.

Ultralow Threshold Lasing from a Continuous-Wave-Pumped SiN/CsPbBr/Ag Thin Film Mediated by the Whispering Gallery Modes of a SiO Microsphere.

Thin-film pervoskite lasers driven by a continuous wave (CW) laser with ultralow thresholds, which is crucial for the development of on-chip electrically driven lasers, have not yet been realized owing to the low excitation power density of the CW laser. Here, we reported the CW-laser-pumped lasing from a thin film of CsPbBr quantum dots (QDs) sandwiched by a SiN and a Ag thin film and mediated by the whispering gallery modes of a SiO microsphere. The stable photoluminescence from CsPbBr QDs with a quantum efficiency of ∼45% is realized by encapsulating with a thin SiN film.

Highly efficient nonlinear optical emission from a subwavelength crystalline silicon cuboid mediated by supercavity mode.

The low quantum efficiency of silicon (Si) has been a long-standing challenge for scientists. Although improvement of quantum efficiency has been achieved in porous Si or Si quantum dots, highly efficient Si-based light sources prepared by using the current fabrication technooloy of Si chips are still being pursued. Here, we proposed a strategy, which exploits the intrinsic excitation of carriers at high temperatures, to modify the carrier dynamics in Si nanoparticles.

Comprehensive analyses reveal the carcinogenic and immunological roles of ANLN in human cancers.

Background: Anillin (ANLN) is an actin-binding protein that is essential for cell division and contributes to cell growth and migration. Although previous studies have shown that ANLN is related to carcinogenesis, no pan-cancer analyses of ANLN have been reported. Accordingly, in this study, we evaluated the carcinogenic roles of ANLN in various cancer types using online databases.

Excitation-Power-Dependent Upconversion Luminescence Competition in Single β-NaYbF:Er Microcrystal Pumped at 808 nm.

Controlling the upconversion luminescence (UCL) intensity ratio, especially pumped at 808 nm, is of fundamental importance in biological applications due to the water molecules exhibiting low absorption at this excitation wavelength. In this work, a series of β-NaYbF:Er microrods were synthesized by a simple one-pot hydrothermal method and their intense green (545 nm) and red (650 nm) UCL were experimentally investigated based on the single-particle level under the excitation of 808 nm continuous-wave (CW) laser. Interestingly, the competition between the green and red UCL can be observed in highly Yb-doped microcrystals as the excitation intensity gradually increases, which leads to the UCL color changing from green to orange.

Greatly Enhanced Plasmon-Exciton Coupling in Si/WS/Au Nanocavities.

A strong light-matter interaction is highly desirable from the viewpoint of both fundamental research and practical application. Here, we propose a dielectric-metal hybrid nanocavity composed of a silicon (Si) nanoparticle and a thin gold (Au) film and investigate numerically and experimentally the coupling between the plasmons supported by the nanocavity and the excitons in an embedded tungsten disulfide (WS) monolayer. When a Si/WS/Au nanocavity is excited by the surface plasmon polariton generated on the surface of the Au film, greatly enhanced plasmon-exciton coupling originating from the hybridization of the surface plasmon polariton, the mirror-image-induced magnetic dipole, and the exciton modes is clearly revealed in the angle- or size-resolved scattering spectra.

Multi-Component Collaborative Step-by-Step Coloring Strategy to Achieve High-Performance Light-Responsive Color-Switching.

Light-responsive color-switching materials (LCMs) are long-lasting hot fields. However, non-ideal comprehensive performance (such as color contrast and retention time cannot be combined, unsatisfactory repeatability, and non-automated coloring mode) significantly hinder their development toward high-end products. Herein, the development of LCMs that exhibit long retention time, good color contrast, repeatability, and the property of automatic coloring is reported.