Background: The prognostic significance of long non-coding RNA LINC00657 remains ambiguous, and its role in prostate cancer (PCa) is not well characterized. This study aims to conduct a meta-analysis to clarify the clinical implications of LINC00657 in various malignancies and to assess its impact on PCa.
Methods: A systematic search was conducted across PubMed, Embase, and Web of Science to identify relevant studies.
Purpose: Machine learning (ML) models presented an excellent performance in the prognosis prediction. However, the black box characteristic of ML models limited the clinical applications. Here, we aimed to establish explainable and visualizable ML models to predict biochemical recurrence (BCR) of prostate cancer (PCa).
View Article and Find Full Text PDFHepatobiliary Pancreat Dis Int
April 2020
Some physiological and ethical problems make it difficult to obtain semen samples from adolescents with varicocele (VC) and to directly evaluate their fertility. Therefore we can only rely on indirect methods to assess the influence of VC on the future fertility of the adolescent patients. Most of the VC adolescents may have normal semen parameters in the adulthood.
View Article and Find Full Text PDFObjective: To investigate the correlation of vasectomy with the risk of prostate cancer in Chinese men.
Methods: We systematically searched the databases CNKI, VIP, Wanfang, PubMed, Embase, and Cochrane Library for the literature relating the relationship between vasectomy and the risk of prostate cancer in Chinese males up to December 2014. According to the inclusion and exclusion criteria, two investigators independently selected the eligible publications, evaluated their quality, and extracted relevant information, followed by a meta-analysis with the software STATA 12.