Publications by authors named "Shendong He"
Immun Inflamm Dis
October 2024
Article Synopsis
- Asthma has two main types, T2 high and low, influenced by dendritic cells (DCs) and their autophagy levels, with enhanced autophagy promoting Th2 and reduced autophagy leading to Th17 differentiation.
- Researchers analyzed gene expression data to identify differentially expressed genes (DEGs) in two types of DCs after exposure to allergens, employing various bioinformatics tools to understand the genes involved in asthma regulation.
- The study found significant gene expression changes, identifying 35 hub genes, particularly noting the gene Gngt2, which was elevated in a low asthma model but did not differ significantly in high asthma conditions compared to controls.
