Publications by authors named "Shenbin Pan"
Background: COL10A1 expression was up-regulated and could promote tumor development in pancreatic cancer. As a secreted protein, plasma COL10A1 level was proven to have certain diagnostic efficacy in gastric cancer, breast cancer, and colorectal cancer. It is still unknown whether it has a biomarker role for pancreatic cancer.
View Article and Find Full Text PDFDiagnostic value of methylated branched chain amino acid transaminase 1/IKAROS family zinc finger 1 for colorectal cancer.
World J Gastroenterol
September 2023
Background: The diagnostic value of combined methylated branched chain amino acid transaminase 1 (BCAT1)/IKAROS family zinc finger 1 (IKZF1) in plasma for colorectal cancer (CRC) has been explored since 2015. Recently, several related studies have published their results and showed its diagnostic efficacy.
Aim: To analyze the diagnostic value of methylated BCAT1/IKZF1 in plasma for screening and postoperative follow-up of CRC.
Article Synopsis
- - This meta-analysis investigates how effective and safe mirvetuximab soravtansine (MIRV) is for treating advanced or recurrent ovarian cancer after the first line of therapy.
- - It includes data from seven studies involving 605 patients, showing an objective response rate of 34.2% and an average progression-free survival of about 5.82 months.
- - While MIRV demonstrated efficacy, it also had a high overall adverse event rate of 87.4%, with common side effects including vision blurring, nausea, and diarrhea, but it is considered a promising option for patients with platinum-resistant ovarian cancer.