Zhejiang Da Xue Xue Bao Yi Xue Ban
March 2014
Objective: To determine the enantiomeric impurity contents of domestic timolol maleate in bulk drugs and eye drops.
Methods: Enantiomer impurity of timolol was assayed by chiral high performance liquid chromatography. The chromatographic conditions were as follows:chiralcel OD chiral column (4.