Publications by authors named "Shen-You Shu"
Article Synopsis
- * A study involving 271 liver cirrhosis patients found a sarcopenia prevalence of 27.7%, with various factors like age, physical activity, and nutritional status influencing its occurrence.
- * The research indicates that while age and other factors are associated with sarcopenia, maintaining physical activity and proper nutrition could help improve muscle strength and overall health in cirrhosis patients.
Article Synopsis
- Thymic peptides (TPs) are utilized in the treatment of malignant pleural effusion (MPE), particularly linked to lung cancer, and this review aims to clarify their effectiveness and safety.
- A systematic review of 34 trials revealed that the combination of thymosin and oxaliplatin significantly improves patient outcomes, including complete response rates and overall survival, especially in those with moderate to large effusions and adequate performance status.
- The findings support the use of TPs, especially thymosin with L-OHP, as effective agents for pleurodesis in MPE, demonstrating both positive clinical responses and relatively good safety profiles.
The poliovirus receptor related-1 (PVRL1) gene encodes nectin-1, a cell-cell adhesion molecule (OMIM #600644), and is mutated in the cleft lip with or without cleft palate/ectodermal dysplasia-1 syndrome (CLPED1, OMIM #225000). In addition, PVRL1 mutations have been associated with nonsyndromic cleft lip with or without a cleft palate (NSCL/P) in studies of multiethnic samples. To investigate the possible involvement of this gene in southern Han Chinese NSCL/P patients, we performed (i) a case-control association study, and (ii) a resequencing study.
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