Publications by authors named "Shen-Yan Zhang"

According to statistics, the incidence of liver cancer is increasing yearly, and effective treatment of liver cancer is imminent. For early liver cancer, resection surgery is currently the most effective treatment. However, resection does not treat the disease in advanced patients, so finding a method with a better prognosis is necessary.

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Background: The standardization of quantification data is critical for ensuring the reliability and measurement traceability in the screening of neonatal inherited metabolic disorders. However, the availability of national certified reference materials is limited in China.

Methods: In this study, we developed a series of dried blood spot (DBS) reference materials containing 9 amino acids (AA) and 10 acylcarnitines (AC) for neonatal screening.

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Article Synopsis
  • Liver ischemia-reperfusion injury (IRI) can negatively impact recovery after liver surgery, and the role of inflammation in this damage is highlighted by limited identified biomarkers.
  • Researchers utilized an advanced antibody array to detect inflammatory cytokines at various stages of hepatic IRI in a mouse model, revealing specific changes in cytokine levels between ischemic and sham controls.
  • The study found that some cytokines increased or decreased distinctly during ischemia and reperfusion, suggesting potential new biomarkers for diagnosing and predicting outcomes in hepatic IRI.
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