Tephrosin induces apoptosis of human pancreatic cancer cells through the generation of reactive oxygen species.

Tephrosin is a natural rotenoid isoflavonoid that has been shown to have potent anticancer activities. In this study, we reported the anticancer activity of tephrosin against pancreatic cancer cells. Tephrosin potently suppressed cell viability in various cancer cell lines and promoted apoptosis of PANC-1 and SW1990 pancreatic cancer cells evidenced by enhanced cleavage of caspase-3/-9 and PARP.

The association between red blood cell distribution width and acute pancreatitis associated lung injury in patients with acute pancreatitis.

Background: Red blood cell distribution width (RDW) that describes red blood cell volume heterogeneity is a common laboratory test. Our aim was to focus on the association between RDW and acute pancreatitis associated lung injury (APALI).

Methodology: A total of 152 acute pancreatitis (AP) patients who conformed to the criteria were included in this study.