Publications by authors named "Shen Ziyu"
Objectives: Presbycusis, or age-related hearing loss (ARHL) has been a common disability disease among the elderly population. It is particularly essential to identify the underlying role of related risk factors for ARHL diagnosis and treatment. Observational studies have shown that cardiovascular disease may be a factor in ARHL.
View Article and Find Full Text PDFConventional metal sulfide (SnS) gas-sensitive sensing materials still have insufficient surface area and slow response/recovery times. To increase its gas-sensing performance, MoSnanoflower was produced hydrothermally and mechanically combined with SnSnanoplate. Extensive characterization results show that MoSwas effectively integrated into SnS.
View Article and Find Full Text PDFArticle Synopsis
- The timing of stroke onset is crucial for treatment, but identifying this in unknown onset strokes is challenging due to a lack of reliable methods, leading to inconsistent treatment choices.
- Recent studies suggest that serum biomarkers may help in determining stroke onset time, but no effective specific biomarkers or methods currently exist for unknown onset strokes.
- This study introduces a machine learning approach using XGBoost to analyze serum metabolites, successfully identifying five key metabolites that can detect acute ischemic stroke and estimate its onset time, which may have implications for clinical evaluations and treatment strategies despite being based on animal experiments.
In this paper, the surface texture parameters and distribution patterns are studied by numerical simulation and experiment. First, a three-dimensional micro-textured CFD fluid lubrication model with cavitation effect is established, and different texture arrays are designed to study the influence of different distribution modes on bearing capacity, friction coefficient and pressure distribution of the oil film. Then, the simulation results are further analyzed and verified by the visualized plane slider experimental platform, and the formation rules of cavitation bubbles in the micro-textured array, as well as the influences of the surface shape and different distribution modes of the micro-textured array on the cavitation bubbles are discussed.
View Article and Find Full Text PDFBackground: Aspartate aminotransferase (AST), alanine aminotransferase (ALT) and γ-glutamyl transferase (GGT) measurements are important for the assessment of liver damage. The aim of this study was to define the reference intervals (RIs) for these enzymes in adults, paying attention to standardization of the methods used and careful selection of the reference population.
Methods: AST, ALT and GGT were measured with commercial analytical systems standardized to the IFCC-recommended reference measurement systems.
Background: As with many studies carried out in European countries, a quality assurance program has been established by the National Center for Clinical Laboratories in China (NCCL). The results showed that the external quality assessment significantly improves laboratory performance for quantitative evaluation of hepatitis C virus (HCV) RNA.
Methods: Serum panels were delivered twice annually to the clinical laboratories which performed HCV RNA detection in China.
Article Synopsis
- The study examines the limitations of traditional methods for setting IgE targets in EQA schemes, particularly when dealing with outliers in data sets.
- Researchers found that original data sets were not always normally distributed, and using robust statistical methods for outlier removal resulted in normally distributed data.
- Significant differences were discovered in IgE targets established by traditional versus robust methods, highlighting the need for appropriate statistical approaches to ensure accuracy in target setting.
[Establishment of the first national standards for nucleic acid amplification technology assay for HBV DNA].
Zhonghua Gan Zang Bing Za Zhi
February 2007
Objectives: To establish a Chinese national standard for a nucleic acid test (NAT) for HBV DNA.
Methods: The candidate sample of HBV DNA positive plasma was diluted with HBV-negative human plasma. The sample was lyophilised with a concentration of approximately 300,000 copies/ml.
Background: Since October 1997, an international standard for hepatitis C virus (HCV) nucleic acid amplification technology assay, 96/790, has been available. We compared a series of lyophilized standards with known HCV RNA concentrations against the international standard in fluorescence quantitative PCR detection.
Methods: A series of lyophilized sera were calibrated by ROCHE COBAS AMPLICOR HCV Monitor test against the international standard and sent to various manufacturers to analyse the samples using their own kits.